Search for dissertations about: "cytokines , periodontitis"

Showing result 1 - 5 of 24 swedish dissertations containing the words cytokines , periodontitis.

  2. 1. Vesicle-independent extracellular release and bioactivity of peptidoglycan-associated lipoprotein from Aggregatibacter actinomycetemcomitans

    Author : Maribasappa Karched; Sirkka Asikainen; Ann-Beth Jonsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptidoglycan-associated lipoprotein; outer membrane proteins; immunoproteomics; periodontitis; cytokines; Aggregatibacter actinomycetemcomitans.; Oral microbiology; Oral mikrobiologi;

    Abstract : Aggregatibacter (Actinobacillus) actinomycetemcomitans is a Gram-negative coccobacillus of the Pasteurellaceae family. It is implicated in periodontitis, a common low-grade bacterial infection, but it can also cause non-oral infections. The main aim of this project was to identify and characterize in A. READ MORE

  4. 2. Novel Insights into Inflammatory Disturbed Bone Remodelling

    Author : Elin Kindstedt; Pernilla Lundberg; Östen Ljunggren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone; osteoblast; osteoclast; chemokines; CCL11; periodontitis; rheumatoid arthritis; innate lympoid cells; odontologi; Odontology; immunologi; Immunology; biology; biologi; reumatologi; rheumatology;

    Abstract : Bone is a dynamic tissue that is continuously remodelled, a process that requires equal amounts of osteoclastic bone resorption and osteoblastic bone formation. Inflammation may disturb the equilibrium and result in local and/or systemic bone loss. Negative bone mass balance occurs in several chronic inflammatory diseases, e.g. READ MORE

  5. 3. Importance of bacterial hydrogen sulfide in the pathogenesis of periodontal diseases

    Author : Amina Basic; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hydrogen sulfide; Periodontitis; Gingivitis; IL-1β; IL-18; NLRP3 inflammasome; Oral microbiota; Fusobacterium spp.; Bismuth test; L-cysteine;

    Abstract : Hydrogen sulfide (H2S) is one of many end-products of the proteolytic activities in the subgingival microbiota in patients with periodontal diseases, such as gingivitis and periodontitis. Although H2S is generally regarded as toxic, the mechanisms that underlie its production and its effects on human cells and tissues are poorly understood. READ MORE

  6. 4. Vesicle-mediated and free soluble delivery of bacterial effector proteins by oral and systemic pathogens

    Author : Bernard Thay; Jan Oscarsson; Mikael Rhen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periodontitis; Aggregatibacter actinomycetemcomitans; Staphylococcus aureus; membrane vesicles; vesicle-host cell interaction; protein delivery; molekylärbiologi; Molecular Biology;

    Abstract : Periodontitis, the primary cause of tooth-loss worldwide, is a bacterially induced chronic inflammatory disease of the periodontium. It is associated with systemic conditions such as cardiovascular disease (CVD). However, pathogenic mechanisms of periodontitis-associated bacteria that may contribute to the CVD association are unclear. READ MORE

  7. 5. Insights into the processes preceding the onset of rheumatoid arthritis

    Author : Linda Johansson; Solbritt Rantapää Dahlqvist; Mikael Brink; Felipe Andrade; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; pre-symptomatic individuals; autoantibodies; anti-citrullinated protein peptides antibodies; Epstein-barr virus; neutrophil extracellular traps; periodontitis; Porphyromonas gingivalis; receptor activator of nuclear factor kappa-B ligand; reumatologi; rheumatology;

    Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by the production of anti-citrullinated protein antibodies (ACPA) in the majority of all patients and a persistent inflammation in the synovial tissue leading to joint destruction. The aetiology of RA remains to a large extent unknown but is believed to be a complex interplay between genetic, environmental and stochastic factors. READ MORE