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Showing result 1 - 5 of 20 swedish dissertations matching the above criteria.

  2. 1. Dissecting sterol function during clathrin-dependent endocytosis and cytokinesis in Arabidopsis thaliana

    Author : Márcia Frescatada-Rosa; Markus Grebe; Wolfgang Lukowitz; Umeå universitet; []
    Keywords : Arabidopsis; membrane; sterols; cytokinesis; KNOLLE; endocytosis; clathrin; DRP1A; Developmental Biology; miljömedicinsk utvecklingsbiologi; molekylärbiologi; Molecular Biology; molecular cell biology; molekylär cellbiologi;

    Abstract : Sterols are lipid components of eukaryotic membranes. Alterations of membrane sterol composition perturb the execution of cell division, which in diverse eukaryotes can have severe consequences for development of the organism. Partitioning of the cytoplasm during cell division occurs at the final stage of cell division named cytokinesis. READ MORE

  4. 2. Adhesion-dependent mechanisms regulating mitosis

    Author : Deepesh Kumar Gupta; Staffan Johansson; Kaisa Haglund; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cytokinesis; Centrosome; Septin; Abscission; Mitosis; Integrin; Adhesion; Binucleation; Biokemi; Biochemistry;

    Abstract : Integrin-mediated cell adhesion is required for normal cell cycle progression during G1-S transition and for the completion of cytokinesis. Cancer cells have ability to grow anchorage-independently, but the underlying mechanisms and the functional significance for cancer development are unclear. READ MORE

  5. 3. Mitotic Kinesin-Like Protein 1 (MKLP1/KIF23) in hereditary congenital dyserythropoietic anemia type III and in cancer

    Author : Ann-Louise Vikberg; Irina Golovleva; Monica Holmberg; Masanori Mishima; Pontus Aspenström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alternative splicing; Cell division; COPI; Congenital dyserythropoietic anemia; Cytokinesis; Gene expression; KIF23 protein human; Cancer; MKLP1 protein mouse; Mutation; medicinsk genetik; Medical Genetics;

    Abstract : A hereditary form of autosomal dominant congenital dyserythropoietic anaemiatype III (CDA III) has been reported in four families from Sweden, Argentina, Cuba and USA. CDA III patients might experience signs of mild anaemia and some of them need occasional blood transfusions. READ MORE

  6. 4. Divisive structures : Two billions years of biofilament evolution

    Author : Fredrik Hurtig; Ann-Christin Lindås; Lionel Guy; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Evolution; Archaea; Eukaryogenesis; ESCRT-III; Actin; Profilin; Gelsolin; Asgard; TACK; Sulfolobus; Cell division; Cytokinesis; Cytoskeleton; Heimdallarchaeota; Actin-binding protein; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Our understanding of the functional and regulatory complexity that existed in the eukaryotic progenitor is poor, and investigations have been hindered by our nebulous understanding of where eukaryotes stem from. Recently discovered archaeal lineages with hitherto unseen homology to eukaryotic systems suggest archaea can further our understanding of the eukaryotic cell’s ancestry. READ MORE

  7. 5. Fluorescence Studies of Membranes -- Proteins and Lipids, their Dynamics and Interactions

    Author : Johan Strömqvist; Jerker Widengren; Thorsten Wohland; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fluorescence correlation spectroscopy; cytokinesis; collision theory; protein-protein interactions; lipid dynamics; single-molecule experiment; Biological physics; Biologisk fysik;

    Abstract : In this thesis, fluorescence spectroscopy was utilized to probe protein and lipid dynamics and interactions in their native, or close to native, environments. Thereby insight could be gained into the fundamentals of bacterial cell division and the innateimmune system. A particular focus has been devoted to fluorescence fluctuations. READ MORE