Search for dissertations about: "cytotoxic"

Showing result 21 - 25 of 636 swedish dissertations containing the word cytotoxic.

  2. 21. Modulation of tumor sensitivity to effector mechanisms of cytotoxic lymphocytes

    Author : Kristian Hallermalm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Tumor escape; cytotoxic lymphocytes; interferon-gamma; TNF-alpha; granzyme B; Perforin; Fas ligand;

    Abstract : Today, ample evidence demonstrates a clear role for the immune system in the battle against cancer. However, the relatively high rate of mutation and proliferation of tumor cells, in combination with the selective pressure exerted by the immune system, can potentially lead to the generation of genetically altered tumor cells, which are able to evade recognition by the immune system and continue to grow and form tumors. READ MORE

  4. 22. Cytotoxic Compounds of Plant Origin – Biological and Chemical Diversity

    Author : Petra Lindholm; Anders Backlund; Lars Bohlin; Kristín Ingólfsdóttir; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacognosy; pharmacognosy; cytotoxicity; antitumour; Nuphar alkaloid; cyclotide; thionin; cardiac glycoside; Farmakognosi; Pharmacognosy; Farmakognosi;

    Abstract : The development of resistance by tumour cells to chemotherapeutic agents is a major problem in cancer treatments. One way to counter this is to find compounds with cytotoxic mechanisms other than those of drugs in clinical use today. READ MORE

  5. 23. Nuclear medicine and cytotoxic studies in renal cell cancer

    Author : Maliha Edgren; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  6. 24. Understanding chronic immunodeficiency disorders through assessment of cytotoxic lymphocyte function

    Author : Jakob Theorell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Representing an evolving and diverse group of syndromes, immunodeficiencies can currently be viewed as a spectrum of disorders where a dysfunction of the immune system plays a significant etiologic role. Cytotoxic lymphocytes are immune cells that are pivotal for the eradication of infected and malignant cells. READ MORE

  7. 25. Risks in the chemotherapy process and possibilities for improvement

    Author : AnnSofie Fyhr; Ergonomi och aerosolteknologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medication errors; Cytotoxic drugs; Chemotherapy; Health care; Risk management; Improvements;

    Abstract : Medications are of considerable help if healthcare providers are able to administer them to patients safely and appropriately. The medication use process is complex and a team of professionals – doctors, nurses, and pharmacists – work together with the patient for optimal treatment effect. READ MORE