Search for dissertations about: "dag nyholm"

Found 5 swedish dissertations containing the words dag nyholm.

2. 1. Pharmacotherapy for Parkinson's Disease - Observations and Innovations

   Author : Dag Nyholm; Sten-Magnus Aquilonius; Andrew Lees; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Parkinson s disease; levodopa; pharmacokinetics; infusion; drug delivery systems; electronic patient diary; Neurovetenskap; Neurology; Neurologi; Neurology; Neurologi;

   Abstract : Pharmacotherapy for Parkinson’s disease (PD) is based on levodopa, the most effective dopaminergic drug. The development of motor complications constitutes the major challenge for new or refined therapies. READ MORE

4. 2. Mapping the Huntington's disease process using cerebrospinal fluid analysis

   Author : Valter Niemelä; Anne-Marie Landtblom; Dag Nyholm; Jimmy Sundblom; Edward Wild; Uppsala universitet; []
   Keywords : Neurodegeneration; Huntingtons disease; Neurogenetics; Neuroinflammation; Neurofilament light; tau; Proenkephalin; Neurology; Neurologi;

   Abstract : Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder, caused by a CAG-repeat expansion in the HTT-gene. Today there are no disease-modifying therapies (DMTs), but several promising clinical trials are underway, including therapies that reduce mutant huntingtin expression. READ MORE

5. 3. Botulinum Toxin : Formulation, Concentration and Treatment

   Author : Alma Rystedt; Dag Nyholm; Carl Swartling; Klas Nordlind; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Botulinum toxin; Botox; Dysport; Xeomin; NeuroBloc; Hyperhidrosis; Cervical dystonia; Neurology; Neurologi;

   Abstract : Botulinum toxin (BTX) is used in various fields of medicine, including the treatment of hyperhidrosis and cervical dystonia. Botox®, Dysport®, Xeomin® and NeuroBloc® are commercially available BTX products, which are formulated differently and their dosing units are unique. READ MORE

6. 4. New Approaches for Levodopa Treatment in Parkinson’s Disease

   Author : Marina Senek; Dag Nyholm; Elisabet I Nielsen; Maral Mouradian; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; Pharmacokinetics; Pharmacodynamics; Population modeling; Levodopa; Carbidopa; Entacapone; Microtablets; Intestinal infusion;

   Abstract : Parkinson’s disease (PD) is characterized by degeneration of dopaminergic cells, which results in dopamine depletion. Levodopa is the most effective symptomatic treatment, however, disease progression along with the unfavorable pharmacokinetics of levodopa makes the disease increasingly difficult to treat with time. READ MORE

7. 5. Experiences of pain and associations between pain, disease severity and individual quality of life in people with motor neuron diseases

   Author : Ylva Åkerblom; Pernilla Åsenlöf; Lena Zetterberg; Dag Nyholm; Lena von Koch; Uppsala universitet; []
   Keywords : Amyotrophic lateral sclerosis; motor neuron disease; pain; quality of life; individual quality of life; qualitative content analysis; pain severity; disease severity;

   Abstract : Many people with the incurable and often times fatal motor neuron diseases have pain, but there is lack of knowledge about people’s experiences of living with pain. Further, the correlation between pain and their quality of life is not well understood, and previous studies have not used individual quality of life, namely that people with their own words express what quality of life is. READ MORE