Search for dissertations about: "datorlingvistik"
Showing result 6 - 10 of 36 swedish dissertations containing the word datorlingvistik.
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6. The Multilingual Forest : Investigating High-quality Parallel Corpus Development
Abstract : This thesis explores the development of parallel treebanks, collections of language data consisting of texts and their translations, with syntactic annotation and alignment, linking words, phrases, and sentences to show translation equivalence. We describe the semi-manual annotation of the SMULTRON parallel treebank, consisting of 1,000 sentences in English, German and Swedish. READ MORE
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7. Multivariate design of molecular docking experiments : An investigation of protein-ligand interactions
Abstract : To be able to make informed descicions regarding the research of new drug molecules (ligands), it is crucial to have access to information regarding the chemical interaction between the drug and its biological target (protein). Computer-based methods have a given role in drug research today and, by using methods such as molecular docking, it is possible to investigate the way in which ligands and proteins interact. READ MORE
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8. Modified Glycopeptides Targeting Rheumatoid Arthritis : Exploring molecular interactions in class II MHC/glycopeptide/T-cell receptor complexes
Abstract : Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that leads to degradation of cartilage and bone mainly in peripheral joints. In collagen-induced arthritis (CIA), a mouse model for RA, activation of autoimmune CD4+ T cells depends on a molecular recognition system where T-cell receptors (TCRs) recognize a complex between the class II MHC Aq protein and CII259-273, a glycopeptide epitope from type II collagen (CII). READ MORE
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9. Exploring non-covalent interactions between drug-like molecules and the protein acetylcholinesterase
Abstract : The majority of drugs are small organic molecules, so-called ligands, that influence biochemical processes by interacting with proteins. The understanding of how and why they interact and form complexes is therefore a key component for elucidating the mechanism of action of drugs. READ MORE
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10. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence
Abstract : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. READ MORE