Search for dissertations about: "decidua"

Showing result 1 - 5 of 14 swedish dissertations containing the word decidua.

  1. 1. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

    Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

    Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE

  2. 2. Immune regulation at the foetal-maternal interface; implications for healthy and complicated pregnancies

    Author : Robert Lindau; Jan Ernerudh; Maria Jenmalm; Kristina Nilsson-Ekdahl; Petra Arck; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : For a successful pregnancy, the maternal immune system must acquire tolerance towards the paternal antigens present in the semi-allogeneic foetus. This tolerance is mainly established locally at the foetal-maternal interface, where foetally-derived trophoblasts invade the maternal endometrium (called decidua during pregnancy) and come in close proximity to maternal immune cells. READ MORE

  3. 3. G protein-coupled estrogen receptor 1 (GPER) in the female reproductive tract: from physiology to cancer

    Author : Zuzana Kolkova; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Estrogen effects are mediated either through genomic action involving the classical estrogen receptors, estrogen receptor alpha (ERα) and beta (ERß), which function as transcription factors in the nucleus, or through rapid non-genomic action via receptors associated with plasma membrane. Recently, a member of the G protein-coupled receptor family was ascribed estrogen receptor properties and proposed as a candidate for mediating non-genomic estrogen signaling. READ MORE

  4. 4. MAIT cells in placental tissues and their reconstitution following allogeneic hematopoietic stem cell transplantation

    Author : Martin Solders; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The placenta is a temporary organ of human reproduction. Both the fetus and placenta are covered in a membrane of maternal origin, the decidua. After the 1st trimester, the fetus is supplied with oxygen and nutrients by maternal arterial blood that penetrates the decidua and fills the intervillous space of the placenta. READ MORE

  5. 5. Monoamine transporters in female human reproduction

    Author : Barbara Bottalico; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PMAT; VMAT2; OCT; NET; in-situ hybridization histochemistry; decidualization; human endometrium; placenta; Medicine human and vertebrates ; Monoamine transporters; preeclampsia; histamine; Medicin människa och djur ;

    Abstract : The present study explored the gene and protein expression of the monoamine transporters in human endometrium throughout the menstrual cycle, in early decidua and in placentas from normal as well as preeclamptic pregnancies using in-situ hybridization, real time-PCR, immunohistochemistry and primary tissue cultures. Four distinguishable patterns were observed in the endometrium over the menstrual cycle: (1) epithelial expression of norepinephrine transporter (NET) mRNA, (2) Stromal co- expression of vesicular monoamine transporter 2 (VMAT2) and plasma membrane monoamine transporter (PMAT) mRNAs with maximal intensity in the proliferative phase; (3) increasing epithelial expression of VMAT2 mRNA with a maximum in the late secretory phase; (4) stromal expression of extra-neuronal monoamine transporter (EMT) mRNA with a peak in the early secretory phase. READ MORE