Search for dissertations about: "decidual"

Showing result 1 - 5 of 12 swedish dissertations containing the word decidual.

  2. 1. Local Immune regulation in human pregnancy : with focus on decidual macrophages

    Author : Charlotte Gustafsson Lidström; Christina Ekerfelt; Eva Sverremark-Ekström; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproduction; placenta; leukocyte; ELISPOT; Clinical immunology; Klinisk immunologi;

    Abstract : During pregnancy, the woman carries a fetus partly foreign to her immune system, because of the expression of paternal antigens. Despite this, the fetus is normally tolerated and not rejected, as is often the case with organs in allogeneic transplantations. READ MORE

  4. 2. Immunoregulatory effects of placenta-derived decidual stromal cells

    Author : Tom Erkers; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Decidual stromal cells (DSCs) play a pivotal role in feto-maternal tolerance to prevent rejection of the fetus during pregnancy. This provides a rationale for immunomodulatory stromal cells from the placenta being isolated and used as cellular therapy for inflammatory conditions following hematopoietic stem cell transplantation (HSCT). READ MORE

  5. 3. Immune regulation at the fetal‐maternal interface with focus on decidual macrophages

    Author : Judit Svensson-Arvelund; Jan Ernerudh; Maria Jenmalm; Göran Berg; Siamon Gordon; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : A successful pregnancy requires that the maternal immune system adapts to tolerate the semi-allogeneic fetal-placental unit. This adaptation mainly occurs locally, i.e. at the fetal-maternal interface, where fetal-derived tissues come into close contact with maternal cells in the uterine endometrium (called decidua during pregnancy). READ MORE

  6. 4. Effects of insulin on the decidualization of human endometrial stromal cells : in vitro studies

    Author : Ivika Jakson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hyperinsulinemia is a known characteristic of obesity and polycystic ovary syndrome, two common clinical conditions associated with reproductive problems. However, the underlying mechanisms to reduced fertility are not fully elucidated, and the role of insulin in reproduction needs further investigation. READ MORE

  7. 5. The role of natural killer cells and inflammatory mediators in preeclamptic pregnancies

    Author : Nora Bachmayer; Eva Sverremark-Ekström; Katarina Bremme; Lucia Mincheva-Nilsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; preeclampsia; NK cells; Immunology; Immunologi; immunologi; Immunology;

    Abstract : The maternal immune system must be able to adjust during pregnancy and accept the foetus that expresses paternal antigens. These changes are found both in placenta and circulation, including a mild inflammatory response. NK cells are abundant during the early part of pregnancy in placenta and are thought to be important for placental development. READ MORE