Search for dissertations about: "decorin"

Showing result 11 - 15 of 32 swedish dissertations containing the word decorin.

  2. 11. Development and application of strategies for the analysis of modification patterns in chondroitin and dermatan sulphate

    Author : Fang Cheng; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; reumatologi; muskelsystem; Skelett; Glycosaminoglycan; Proteoglycan; Chondroitin sulphate; dermatan sulphate; Sequencing analysis; Modification pattern.; Skeleton; rheumatology locomotion; muscle system; Metabolism; Biokemi; metabolism;

    Abstract : Chondroitin (CS) and dermatan sulphate (DS) are socalled glycosaminoglycans (GAG) that are covalently attached to various type of proteins forming a subgroup within the diverse proteoglycan (PG) family. The PGs studied in this thesis are mostly extracellularly located and include aggrecan, biglycan and decorin. READ MORE

  4. 12. Functions of small leucine-rich repeat proteoglycans in connective tissues

    Author : Sebastian Kalamajski; Åke Oldbergs forskargrupp; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Biological properties of connective tissues rely heavily on collagen and its use in formation of extracellular networks (matrices) in which cells can live and move. To regulate the process of collagen matrix assembly, the cells secrete small leucine-rich repeat proteoglycans (SLRPs) that bind to collagen and influence its fibril formation. READ MORE

  5. 13. Intracellular processing of pre-a-inhibitor

    Author : Maria Thuveson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; pre-alpha-inhibitor; heavy chain 3; bikunin; intracellular processing; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Pre-α-inhibitor (PαI) is a plasma protein consisting of a 25 and a 75 kDa polypeptide: bikunin and heavy chain 3 (H3), respectively. Both these polypeptides are made by hepatocytes and while passing through the Golgi complex, bikunin, which carries a chondroitin sulfate chain, becomes covalently linked to the C-terminal amino acid residue of H3 via its polysaccharide. READ MORE

  6. 14. Biomolecular Aspects of Flexor Tendon Healing

    Author : Maria Berglund; Monica Wiig; Olof Nilsson; Jan Fridén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flexor tendon healing; Growth factor; Metalloproteinase; Collagen; Proteoglycan; Myofibroblast; Hyaluronan synthase; Mast cell; Hand surgery; Handkirurgi; Orthopaedics; Ortopedi;

    Abstract : Flexor tendon injuries in zone II of the hand (i.e. between the distal volar crease and the distal interphalangeal joint) can be costly for both the afflicted individual and society because of the high cost of a long rehabilitation period, complicated by tendon ruptures or scarring with adhesion formation, causing impaired range of motion. READ MORE

  7. 15. Functional and molecular aspects of the glomerular barrier

    Author : Anna Björnson Granqvist; Göteborgs universitet; []
    Keywords : glomerular endothelium; glycocalyx; podocyte; proteoglycan; glycosaminoglycans; nephrotic syndrome;

    Abstract : The kidneys are crucial for maintaining a normal salt-water balance in the body, which is a prerequisite for life. They do that by filtering 180 liters of plasma per day across the highly permselective glomerular barrier and reabsorbing 99 % of the filtrate. READ MORE