Search for dissertations about: "decorin"

Showing result 16 - 20 of 32 swedish dissertations containing the word decorin.

  2. 16. Endocrine and neuronal interactions in human cervical ripening

    Author : Ylva Stjernholm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Estrogen receptor; progesterone receptor; IGF-I mRNA; thioredoxin; PGP 9.5. neuropeptides; dendritic cells;

    Abstract : Objective: To evaluate the hormonal and neuronal environment in human cervix during pregnancy and parturition. Methods: Cervical biopsy specimens were obtained transvaginally, and serum samples were drawn simultaneously. READ MORE

  4. 17. Tissue repair in lung disorders

    Author : Annika Andersson Sjöland; Lungbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The remodeling phase of tissue repair in lung disorders such as idiopathic pulmonary disease, asthma, obliterative bronchiolitis, and after lung transplantation is not well understood. One of the key players in fibrosis is the fibroblast and its progenitor, the fibrocyte. READ MORE

  5. 18. Unraveling pathogenic proteins and pathways in Alzheimer disease : a focus on proteomics

    Author : Hazal Haytural; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer disease (AD) is a multifactorial and complex neurodegenerative disorder. To date, different mechanisms, such as impairment of synaptic, mitochondrial and autophagic function, neuroinflammation and many more, are found to disrupt cellular homeostasis in AD brains. READ MORE

  6. 19. Aspects of the glomerular barrier in healthy and diabetic kidneys

    Author : Marie Jeansson; Göteborgs universitet; []
    Keywords : glomerular size and charge selectivity; isolated perfused kidney; electron microscopy; glycocalyx; diabetic nephropathy; NOD mice;

    Abstract : Each day 180 liters of plasma is filtered in the kidneys. Under normal conditions, the glomerular barrier restricts the passage of macromolecules such as albumin while it is highly permeable to water and small solutes. Proteinuria is a hallmark of renal disease and reflects impairment of the glomerular barrier. READ MORE

  7. 20. Tissue remodelling in pulmonary fibrosis linked to 5-HT2 receptor activation

    Author : Anna Löfdahl; Lungbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Serotonin 5HT ; Serotonin class 2 receptor antagonist; Fibroblast; Pulmonary fibrosis; Extracellular matrix ECM ;

    Abstract : After an injury, an immediate reparative response is triggered to replace the damaged tissue, however, in fibrosis, cells remain active despite wound resolution causing a steady build-up of fibrotic tissue. In pulmonary fibrosis,there is a constant regeneration and remodelling of lung tissue where the thin architecture of alveoli become thickened, hampering efficient diffusion of oxygen, as seen in diseases like idiopathic pulmonary fibrosis (IPF). READ MORE