Search for dissertations about: "deep levels"

Showing result 21 - 25 of 246 swedish dissertations containing the words deep levels.

  2. 21. Development of a Method to Measure Plasma Levels of Activated Protein C in Complex with Protein C Inhibitor

    Author : Karin Strandberg; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C inhibitor; activated protein C; hypercoagulability; deep vein thrombosis; Clinical chemistry; myocardial infarction; Klinisk kemi;

    Abstract : Acute myocardial infarction (MI) and deep venous thrombosis (DVT) are conditions caused by thrombus formation with activation of the coagulation system. The plasma concentration of the complex between activated protein C (APC) and protein C inhibitor (PCI), APC–PCI complex is increased in such states. READ MORE

  4. 22. Diving into short linear motifs : Large-scale identification of endogenous and host-pathogen protein-protein interactions and further characterized by deep mutational scanning

    Author : Caroline Benz; Ylva Ivarsson; Birthe B. Kragelund; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein-protein interactions; short linear motif; endogenous interactions; host-pathogen; viral hijacking; deep mutational scanning; Biokemi; Biochemistry;

    Abstract : Short linear motifs (SLiMs) are protein-protein interaction sites that play an essential role in distinct cellular processes. Those interactions are challenging to capture by common high-throughput methods. READ MORE

  5. 23. Ultra-deep characterization of viral quasispecies in HIV infection

    Author : Charlotte Hedskog; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : HIV-1 has the ability to rapidly diversify and adapt to changes in its environment, such as evading the host immune response, altering cell tropism, and developing resistance to antiretroviral drugs. Minority HIV-1 variants have been shown to be of clinical significance, especially those with non-nucleoside reverse transcriptase inhibitor (NNRTI) drug resistance mutations or determinants of CXCR4 phenotype (X4-virus). READ MORE

  6. 24. G-equivariant convolutional neural networks

    Author : Jimmy Aronsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; deep learning; induced representations; homogeneous vector bundles; convolutional neural networks; homogeneous spaces; symmetry;

    Abstract : Over the past decade, deep learning has revolutionized industry and academic research. Neural networks have been used to solve a multitude of previously unsolved problems and to significantly improve the state-of-the-art on other tasks, in some cases reaching superhuman levels of performance. READ MORE

  7. 25. Genomic and transcriptomic profiles in chronic hepatitis B infection

    Author : Johan Ringlander; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; hepatitis delta virus; integration; deep sequencing; cirrhosis; HCC;

    Abstract : Chronic infection with hepatitis B virus (HBV) affects >250 million people globally and is the most common cause of hepatocellular carcinoma and liver cirrhosis worldwide. Approximately one million deaths each year are attributed to HBV infection. The virus is adapted to the human host and has developed mechanisms to evade immunity. READ MORE