Search for dissertations about: "defective"

Showing result 1 - 5 of 343 swedish dissertations containing the word defective.

  2. 1. How does the technical status of medical ultrasound equipment affect image quality? Studies based on human observer experiments and a novel method for automatic detection of defective transducers

    Author : Robert Lorentsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ultrasound; defective transducer; image quality;

    Abstract : Ultrasound as an imaging modality has a fundamental role in modern healthcare. The equipment, especially transducers, is fragile and handled daily, and transducers are known to sometimes become defective. The overall aim of this thesis was to evaluate how the technical status of the equipment affects clinical image quality. READ MORE

  4. 2. Pathophysiology and treatment of defective insulin secretion in diabetes

    Author : Anders Rosengren; Diabetes - öpatofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic beta-cells; stem cells; genetics; exocytosis; Adra2a; PACAP; GLP-1; Physiology; Fysiologi; secreting systems; Endocrinology; diabetology; Endokrinologi; insulin secretion; Diabetes mellitus; sekretion; diabetologi;

    Abstract : Defective insulin secretion is a central feature in diabetes mellitus and results from reduced pancreatic beta-cell mass as well as aberrant beta-cell function. The pathophysiology of diabetes is incompletely known, but a strong hereditary component is suggested. READ MORE

  5. 3. Mechanisms of defective insulin secretion in type 2 diabetes

    Author : Taman Mahdi; Diabetes - öpatofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; Insulin secretion; TCF7L2; ADRA2A; KCNQ1; SFRP4; interleukin-1B;

    Abstract : Defective insulin secretion from the pancreatic B-cells is a central feature in type 2 diabetes (T2D). There is a strong hereditary component in type T2D, but the underlying pathophysiology remains largely unknown. READ MORE

  6. 4. Early oncogenic events and defective apoptosis in prostate cancer

    Author : Xiaolei Fang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Prostate cancer; HGPIN; ezrin; pim-1; XAF1; apoptosis; DNA methylation; immunohistochemistry; FISH;

    Abstract : Prostate cancer is one of the most common malignancies in males in the Western world. Although the mechanisms are unclear, it is generally believed that the accumulation of genetic alterations leads to the tumor formation. READ MORE

  7. 5. Molecular regulation of thyroid development. New mechanisms of normal and defective morphogenesis

    Author : Henrik Fagman; Göteborgs universitet; []
    Keywords : thyroid; congenital hypothyroidism; thyroid dysgenesis; cadherins; pharyngeal arch arteries; Shh; Tbx1;

    Abstract : Congenital hypothyroidism (CH) is untreated a major cause of mental retardation. The majority of cases are due to malformations of the gland (dysgenesis). Little is known of molecular mechanisms regulating thyroid morphogenesis. READ MORE