Search for dissertations about: "defined daily doses"

Showing result 1 - 5 of 16 swedish dissertations containing the words defined daily doses.

  2. 1. On the clinical use of digitalis : with reference to its prescription, maintenance therapy, intoxication and the patient's knowledge

    Author : Kurt Boman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Digitalis; prescribing habits; dosages; defined daily doses; geriatric patients; maintenance therapy; withdrawal; intoxication; serum digitalis concentration; patient s knowledge;

    Abstract : Digitalis in one of the most frequently prescribed drugs, especially to elderly people. The prescription of cardiac glucosides (1978) was studied by using statistics from Apoteksbolaget (the National Corpora­tion of Swedish Pharmacies). READ MORE

  4. 2. The importance of the CYP2C19 polymorphism for disposition and effects of omeprazole treatment

    Author : Mohamed Sagar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Omeprazole; CYP2C19; H. pylori; gastrin; intragastric pH; vitamin B12;

    Abstract : CYP2C19, catalyzes the metabolism of omeprazole and several other drugs. About 3% of Caucasians are poor metabolizers (PM) of these drugs. The goal of this thesis was to evaluate the importance of CYP2C19 polymorphism for disposition and clinical effects of omeprazole treatment in healthy subjects and in patients with acid related disorders. READ MORE

  5. 3. Benzodiazepine and opioid dependence. Clinical and meta-analytical studies

    Author : Björn Axel Johansson; Kliniskt Centrum för Hälsofrämjande Vård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinical psychology; psychosomatics; Psychiatry; meta-analysis; opioid dependence; RCT; naltrexone; prescribed drugs; maintenance treatment; methadone; withdrawal symptoms; benzodiazepine dependence; DSM-IV; Psykiatri; klinisk psykologi; psykosomatik;

    Abstract : The thesis contains 4 papers, two clinical studies and two meta-analyses. In the BZD taper study (Paper I) 21 BZD dependent (DSM-IV) patients were included for a 10-day inpatient detoxification. The average defined daily dose (DDD) was 4.7 doses. READ MORE

  6. 4. A pharmacokinetic and pharmacodynamic study of an antiepileptic drug (lamotrigine) in young patients with drug-resistant generalized epilepsy

    Author : Ann-Sofie Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : High-performance liquid chromatography; Antiepileptic drugs; Therapeutic drug monitoring; Lamotrigine; Carbamazepine; Epilepsy; Children; Lennox-Gastaut; Efficacy; CSF; [gamma]aminobuturic acid; Glutamate; Aspartate; Glycine; EEG;

    Abstract : The purpose of the present study was to investigate the safety and efficacy of lamotrigine in young patients with drug-resistant generalised epilepsy. This group of patients is difficult to study due to a high seizure frequency, comorbidity and the frequent use of polytherapy. READ MORE

  7. 5. Suicide : a pharmacoepidemiological database study in the region Friuli Venezia Giulia, Italy

    Author : Giulio Castelpietra; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Aims: The objective of this thesis is to examine the relationship between suicide and health care in Italy’s Friuli Venezia Giulia (FVG) region. First, it explores the correlation between suicide rates and antidepressant sales. READ MORE