Search for dissertations about: "degeneration"
Showing result 1 - 5 of 375 swedish dissertations containing the word degeneration.
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1. The Vicissitudes of Corruption : Degeneration - transgression - jouissance
Abstract : In a time when corruption is receiving increasing media coverage and when many claim to wage a war on corruption, this book brings up the need for a problematisation and an increased understanding of the different manifestations – the vicissitudes – of corruption and also what measures are taken against it. The book advances the claim that corruption is tightly related to modernity and particularly to a transgression of the public / private dichotomy. READ MORE
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2. Functional consequences of dopaminergic degeneration : Clinical and experimental studies using a novel stabilizer of dopaminergic systems
Abstract : Since the introduction of levodopa for the treatment of Parkinson's disease (PD) 30 yearsago, the emergence of motor complications, such as levodopa-induced dyskinesias (LID), hasbeen a major clinical problem in advanced stages of the disease. Clinical and preclinical studieshave revealed a number of functional changes in the dopaminergic system that may be ofimportance for the emergence of LIDs. READ MORE
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3. rd1 Photoreceptor Degeneration: Photoreceptor Rescue and Role of Metalloproteases in Retinal Degeneration
Abstract : The thesis is focused on an attempt to delay photoreceptor cell death in the rd1 mouse using Lens Epithelium Derived Growth Factor (LEDGF), Glutathione S-Transferase mu (GST-?? and Glutathione S-Transferase alpha (GST-?? in an organ culture paradigm as well as the role of metalloproteases (MMPs) and their tissue inhibitors in photoreceptor degeneration (TIMPs). The rd1 mouse model displays a retina degeneration which starts around day 10 with rod photoreceptor cell death. READ MORE
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4. Molecular Mechanisms of Frontotemporal Lobar Degeneration
Abstract : The aim of this thesis was to identify genetic factors involved in frontotemporal lobar degeneration (FTLD), a neurodegenerative disorder clinically characterised by a progressive change in personality, behaviour and language. FTLD is a genetically complex disorder and a positive family history is found in up to 40% of the cases. READ MORE
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5. Cell Therapy in lntervertebral Disc Degeneration
Abstract : Background: Chronic low back pain (LBP) is the leading cause of disability worldwide. Intervertebral disc degeneration (IDD) is central in the pathogenesis. The injection of bone marrow-derived mesenchymal stromal cells (BM-MSCs) into degenerate intervertebral discs (IVDs) has been proposed as an alternative therapy. READ MORE