Search for dissertations about: "degenerative disc disease"

Showing result 1 - 5 of 14 swedish dissertations containing the words degenerative disc disease.

  1. 1. Cell Therapy in lntervertebral Disc Degeneration

    Author : Papadimitriou Nicolaos; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Low back pain; Mesenchymal stromal cell; Intervertebral disc; Intervertebral disc degeneration; Degenerative disc disease; Cell therapy;

    Abstract : Background: Chronic low back pain (LBP) is the leading cause of disability worldwide. Intervertebral disc degeneration (IDD) is central in the pathogenesis. The injection of bone marrow-derived mesenchymal stromal cells (BM-MSCs) into degenerate intervertebral discs (IVDs) has been proposed as an alternative therapy. READ MORE

  2. 2. Novel Materials and Implant Designs for the Treatment of Degenerative Disc Disease

    Author : Salim Ghandour; Cecilia Persson; Donal McNally; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Topology Optimization; Spine; Intervertebral Disc; Papain; Additive Manufacturing; Biomechanics; Bone Cement; PMMA; Calcium Phosphate; Cage; Fusion; Engineering Science with specialization in Biomedical Engineering; Teknisk fysik med inriktning mot medicinsk teknik;

    Abstract : The overarching objective of this thesis was to develop intervertebral implants for degenerated discs through design, fabrication, and mechanical validation. The research had four primary aims, each addressing different facets of implant development. READ MORE

  3. 3. Outcome after surgery for isthmic spondylolisthesis and degenerative disc disease

    Author : Peter Endler; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Individuals with isthmic spondylolisthesis and lumbar degenerative disc disease may have low back and leg pain. Those with persistent symptoms non-responsive to conservative treatment are sometimes treated surgically. Various surgical methods have been introduced, but long-term outcome comparisons are scarce. READ MORE

  4. 4. On Total Disc Replacement

    Author : Svante Berg; Hans Tropp; Tycho Tullberg; Claes Olerud; Gunnar B.J. Andersson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Low back pain consumes a large part of the community’s resources dedicated to health care and sick leave. Back disorders also negatively affect the individual leading to pain suffering, decreased quality-of-life and disability. READ MORE

  5. 5. Measurement of outcome in lumbar spine surgery : Validity and interpretability of frequently used outcome measures in the Swespine register

    Author : Catharina Parai; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spine register; disc herniation; spinal stenosis; degenerative disc disorder; patient-reported outcome measure; Global Assessment; minimal important change; smallest detectable change; retest reliability; non-response to follow-up; attrition; measurement of change;

    Abstract : BACKGROUND. The purpose of elective lumbar spine surgery is mainly to reduce pain and to improve physical function and quality of life. The quality and results of the interventions are monitored in the Swedish spine register, Swespine. READ MORE