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Found 5 swedish dissertations matching the above criteria.

  1. 1. Fatty Acid Desaturase Activities in Metabolic Syndrome and Cardiovascular Disease : Special Reference to Stearoyl-CoA-Desaturase and Biomarkers of Dietary Fat

    Author : Eva Warensjö; Ulf Risérus; Bengt Vessby; Tommy Cederholm; David Laaksonen; Uppsala universitet; []
    Keywords : Nutrition; Fatty acids; Dietary fat; Biomarker; Metabolic Syndrome; Mortality; Obesity; Insulin Sensitivity; Epidemiology; Estimated desaturase activities; Stearoyl-CoA-desaturase; delta-6-desaturase; delta-5-desaturase; Single Nucleotide Polymorphism; Dietary Intervention; Rapeseed oil; Saturated fat; SCD1; Näringslära;

    Abstract : The development of the metabolic syndrome (MetS) and cardiovascular diseases have been suggested to be influenced more by the quality than the amount of dietary fat. The FA composition of serum lipids may be used as biomarkers of dietary fat quality. READ MORE

  2. 2. Intestinal Gene Expression Profiling and Fatty Acid Responses to a High-fat Diet

    Author : Jonathan Cedernaes; Helgi B Schiöth; Robert Fredriksson; Anders Jacobsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adhesion GPCR; delta-5 desaturase; delta-6 desaturase; desaturase index; Diet-induced obesity; estimated desaturase activity; fatty acid composition; gas chromatography; gastrointestinal tract; G-protein coupled receptor; high-fat diet; intestine; linoleic acid; liver; mRNA expression; palmitoleic acid; plasma; phospholipids; proximodistal; RT-qPCR; solute carrier; SCD-1; SCD-16; SCD-18; stearoyl-CoA desaturase; subcutaneous adipose tissue; subsection; triacylglycerols.; Medical Genetics; Medicinsk genetik; Nutrition; Nutrition; Näringslära; Nutrition;

    Abstract : The gastrointestinal tract (GIT) regulates nutrient uptake, secretes hormones and has a crucial gut flora and enteric nervous system. Of relevance for these functions are the G protein-coupled receptors (GPCRs) and the solute carriers (SLCs). READ MORE

  3. 3. Interaction between dietary factors and genetic risk for lipoprotein traits and cardiovascular disease

    Author : Sophie Hellstrand; Diabetes - kardiovaskulär sjukdom; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diet; polyunsaturated fatty acids; diet quality index; fatty acid desaturase; blood lipids; lipoproteins; polymorphisms; genetic risk score; gene-diet interaction; cohort; epidemiology; cardiovascular disease;

    Abstract : In previous studies, a high quality diet has been associated with a reduced risk of cardiovascular disease (CVD) compared to a low diet quality, and specific “healthy” diet components, such as polyunsaturated fatty acids (PUFAs), have been hypothesized to reduce the risk of CVD. However, results from epidemiological studies have been conflicting. READ MORE

  4. 4. Early steps of Eicosanoid precursor absorption and tissue distribution

    Author : Tor Melin; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipids; mebran; steroider; Lipider; steroids; membranes; Gastro-enterology; Gastroenterologi;

    Abstract : Eicosanoids are important for a wide range of physiological and pathophysiological processes.How their essential fatty acid precursors are absorbed and tissue distributed is not well charactherized. When given orally to rats, arachidonic acid (20:4) was retained in the small intestine to a larger extent than linoleic acid (18:2). READ MORE

  5. 5. On diet in ankylosing spondylitis

    Author : Björn Sundström; Solveig Wållberg-Jonsson; Gunnar Johansson; Margaretha Haugen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diet; ankylosing spondylitits; omega-3; cardiovascular; reumatologi; rheumatology;

    Abstract : The aim of this thesis was to examine the role of diet in ankylosing spondylitis (AS). Patients were examined in: i) a postal questionnaire survey of dietary habits and gastrointestinal (GI) symptoms; ii) a study on biomarkers of diet and disease activity; iii) a comparison of cardiovascular risk factors with the general population using data from the Västerbotten Intervention Programme (VIP), and; iv) a 21-week omega-3 fatty acid supplementation study regarding the effects on disease activity. READ MORE