Search for dissertations about: "demyelinating disease"

Showing result 1 - 5 of 37 swedish dissertations containing the words demyelinating disease.

  2. 1. Respiratory burst and severity of demyelinating diseases

    Author : Natalia Mossberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurologi; immunologi; Guillain-Barré; Multiple sclerosis; respiratory burst;

    Abstract : Multiple sclerosis (MS) and the Guillain-Barré syndrome (GBS) are tissue-specific inflammatory diseases of the central and the peripheral nervous system, respectively. A contemporary analysis infers that these are complex autoimmune disorders. READ MORE

  4. 2. Radiological studies of LMNB1-related autosomal dominant leukodystrophy and Marinesco-Sjögren syndrome

    Author : Johannes Finnsson; Raili Raininko; Eva Kumlien; Isabella Björkman-Burtscher; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukoencephalopathies; hereditary central nervous system demyelinating diseases; autonomic dysfunction; adult-onset; neuromuscular disease; pediatric; neuro-ophtalmology; ataxia;

    Abstract : There are approximately 6000 to 8000 rare diseases, each with a prevalence of less than 1 / 10 000, but in aggregate affecting 6 to 8% of the population. It is important to evaluate disease development and progression to know the natural course of any disease. READ MORE

  5. 3. Neurofilaments as biomarkers of neuronal damage

    Author : Fani Pujol-Calderón; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofilaments; biomarker; neurodegenerative disease; stroke;

    Abstract : Different neurodegenerative diseases have overlapping symptomatology and pathology and have thus become a challenge to modern medicine to achieve a correct diagnosis. The aim of the thesis was to evaluate the use of neurofilaments as biomarkers of neuronal damage by testing their ability to discriminate between different neurodegenerative diseases as well as assessing whether higher neurofilments predict a poorer clinical outcome in ischemic stroke. READ MORE

  6. 4. Deciphering and fine-tuning of myeloid cells in CNS demyelinating conditions

    Author : Keying Zhu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Demyelination in the central nervous system (CNS) is a characteristic of various neurological disorders, such as multiple sclerosis (MS), neuromyelitis optica (NMO), subacute combined degeneration (SCD), tabes dorsalis (syphilitic myelopathy), and more. Although the causes vary, CNS demyelination is often associated with a significant buildup of inflammatory activated myeloid cells, mainly consisting of CNS resident microglia and infiltrating monocyte-derived macrophages. READ MORE

  7. 5. Demyelinating conditions regulated by ROS pathways outside and inside the brain

    Author : Karl Carlström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic inflammatory condition of the central nervous system with immune-mediated damage on myelinated nerve tracts. Accumulating evidence support a role for autoreactive T-lymphocytes orchestrating immuneattacks on myelinating oligodendrocytes (OLs). READ MORE