Search for dissertations about: "dendrites"

Showing result 1 - 5 of 70 swedish dissertations containing the word dendrites.

  2. 1. Dendritic and axonal ion channels supporting neuronal integration : From pyramidal neurons to peripheral nociceptors

    Author : Marcus Petersson; Erik Fransén; Theodore Cummins; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ion channels; computational modeling; simulations; dendrites; axons; TRP; hippocampus; C-fiber nociceptors; pain;

    Abstract : The nervous system, including the brain, is a complex network with billions of complex neurons. Ion channels mediate the electrical signals that neurons use to integrate input and produce appropriate output, and could thus be thought of as key instruments in the neuronal orchestra. READ MORE

  4. 2. Mechanisms of traumatic brain injury in the rat : Morphological consequences and neurotrophic responses

    Author : Anders Lewén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Cortical contusion injury; TBI; neurons; axons; dendrites; APP; MAP2; BMPR-II; ActR-I; trkB; c-fos; BDNF; PACAP; TUNEL; TGFs; serine threonine; bone morphogenetic protein; neuropeptides; reactive oxygen species; ROS; apoptosis; Neurovetenskap; Neurology; Neurologi; Neurosurgery; neurokirurgi;

    Abstract : Traumatic brain injury is a major cause of death and disability in the Western world. especially in young people. Understanding the pathophysiology of traumatic brain injury is the basis for further development of better therapeutic strategies for such patients. READ MORE

  5. 3. Targeting of viral proteins to axons and dendrites

    Author : Katarzyna Weclewicz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In the thesis distribution of different proteins of enveloped and non-enveloped viruses was studied in neurons, which are polarized cells with an axonal and a somatodendritic domain. Such studies may give better insight not only into virus spread within neuronal populations and selective changes in infected neurons as a consequence of the spread, but they may also contribute to an understanding of the basic sorting mechanisms, which are responsible for asymmetric targeting of macromolecules to the pre- and postsynaptic regions in a nerve cell. READ MORE

  6. 4. Endoplasmic reticulum function in dendrites and dendritic spines of hippocampal neurons

    Author : Ai Na Ng; Sektion IV; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endoplasmic reticulum; primary culture; dendritic spines; live cell imaging; STIM1; carbachol; store-operated calcium entry; 3; familial Alzheimer s disease; 5-dihyroxyphenyglycine;

    Abstract : In the hippocampus, dendritic spines are compartmentalized postsynaptic micro-domains in the excitatory synapse. Subsets of bigger and mushroom-shaped hippocampal dendritic spines contain tubules and cisterns of endoplasmic reticulum (ER) that are connected to the soma and dendrites of the neuron. READ MORE

  7. 5. Non-linear synaptic integration on dendrites of striatal medium-spiny neuron : a computational study

    Author : Kai Du; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Striatum is the main input nucleus of basal ganglia. Medium-spiny neurons (MSNs), the principal neurons of the striatum, receive convergent excitatory inputs from cortex and thalamus, thus “gate” the information flow to the basal ganglia. READ MORE