Search for dissertations about: "dendritic cell"

Showing result 1 - 5 of 326 swedish dissertations containing the words dendritic cell.

  1. 1. Signaling determinants in Trojan horse-mediated dissemination of Toxoplasma gondii

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Einar B. Ólafsson; Antonio Barragan; Eva Frickel; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apicomplexa; leukocyte motility; dendritic cell; amoeboid migration; host-parasite interactions; podosome; integrin; ITGB1; ECM; MAT; TIMP; MMP; MAPK; Erk; RTK; HGFR; Ras; calcium; VDCC; VGCC; calmodulin; CaMkII; CD63; FAK; SRC; Pi3k; hypermigration; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Toxoplasma gondii is an obligate intracellular parasite that infects all warm-blooded vertebrates including one third of the global human population. While infection is typically asymptomatic in healthy human hosts, reactivated and acute infection in immunosuppressed or immunecompromised individuals can lead to lethal toxoplasmic encephalitis After ingestion, the parasite crosses the intestinal epithelium and rapidly achieves systemic dissemination, ultimately establishing chronic infection in the brain. READ MORE

  2. 2. Towards a detailed understanding of the red blood cell storage lesion and its consequences for in vivo survival following transfusion

    University dissertation from Umeå : Umeå universitet

    Author : Andreas Hult; Christer Malm; Per-Arne Oldenborg; Martin L. Olsson; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Red blood cell; erythrocyte; transfusion; macrophage; phagocytosis; storage lesion; eryptosis; Class A scavenger receptor; transfusion medicine; transfusionsmedicin;

    Abstract : Red blood cells (RBCs) are vital for oxygen delivery to tissues and constitute the vast majority of all cells in blood. After leaving the red bone marrow as mature cells, RBCs have a lifespan of approximately 120 days before they are removed from the circulation by macrophages, mainly in the spleen and liver. READ MORE

  3. 3. Defining the role of CD47 and SIRPα in murine B cell homeostasis

    University dissertation from Umeå : Umeå University

    Author : Shrikant S Kolan; Per-Arne Oldenborg; Mikael Karlsson; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; CD47; SIRPα; Follicular B cell; Marginal zone macrophages; immunologi; Immunology;

    Abstract : B cell development is a highly organized process, which commences in the fetal liver during embryogenesis and in the bone marrow (BM) after birth. Surface IgM+ immature B cells emigrate from the BM via the blood stream to the spleen and finally differentiate into conventional mature follicular B (FoB) cells and marginal zone (MZ) B cells. READ MORE

  4. 4. Dendritic cell presentation of type II collagen

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Meirav Holmdahl; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; chromosome 2; arthritis; proteases; antigen presentation; Dendritic cell; type II collagen;

    Abstract : Type II collagen (CII) is the main protein component of cartilage and immune recognition of CII plays a critical role for the development of collagen induced arthritis (CIA), a widely used animal model for rheumatoid arthritis (RA). Antigen presentation is an important requirement for the immune response, the more efficient presentation of the antigen the better tolerance will be induced and thereby protect against arthritis. READ MORE

  5. 5. Leishmania donovani Lipophosphoglycan Modulation of Macrophage and Dendritic Cell Function

    University dissertation from Institutionen för molekylär och klinisk medicin

    Author : Katarina Tejle; Birgitta Rasmusson; Karl-Eric Magnusson; Olle Stendahl; Marita Troye-Blomberg; [2006]
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Lipophosphoglycan; Leishmania donovani; macrophage; actin; phagocytosis; PKC alpha; dendritic cell; VETERINARY MEDICINE Microbiology and immunology; VETERINÄRMEDICIN Mikrobiologi och immunologi;

    Abstract : Leishmania donovani is a blood-borne tropicial parasite, which infects humans through bites by Phlebotomus sandflies. The parasite survives and multiplies inside macrophages in inner organs, and causes the deadly disease visceral leishmaniasis (Kala-Azar). READ MORE