Search for dissertations about: "dendritic integration"

Showing result 1 - 5 of 9 swedish dissertations containing the words dendritic integration.

  2. 1. Beyond AMPA and NMDA: Slow synaptic mGlu/TRPC currents : Implications for dendritic integration

    Author : Marcus Petersson; Erik Fransén; Abdel El Manira; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transient receptor potential; TRP; metabotropic glutamate receptor; mGlu1 5; dendritic integration; synaptic activation; temporal summation; low-frequency; entorhinal cortex; mathematical model; computational neuroscience; Computer science; Datavetenskap;

    Abstract : In order to understand how the brain functions, under normal as well as pathological conditions, it is important to study the mechanisms underlying information integration. Depending on the nature of an input arriving at a synapse, different strategies may be used by the neuron to integrate and respond to the input. READ MORE

  4. 2. A-type Potassium Channels in Dendritic Integration : Role in Epileptogenesis

    Author : Jenny Tigerholm; Erik Fransén; Fredrik Elinder; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; epileptogenesis; fast ripples; synchronicity; dendritic potentials; transient A–type potassium current; KV 4.2; Computer and systems science; Data- och systemvetenskap;

    Abstract : During cognitive tasks, synchronicity of neural activity varies and is correlated with performance. However, there may be an upper limit to normal synchronised activity – specifically, epileptogenic activity is characterized byexcess spiking at high synchronicity. READ MORE

  5. 3. Dendritic and axonal ion channels supporting neuronal integration : From pyramidal neurons to peripheral nociceptors

    Author : Marcus Petersson; Erik Fransén; Theodore Cummins; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ion channels; computational modeling; simulations; dendrites; axons; TRP; hippocampus; C-fiber nociceptors; pain;

    Abstract : The nervous system, including the brain, is a complex network with billions of complex neurons. Ion channels mediate the electrical signals that neurons use to integrate input and produce appropriate output, and could thus be thought of as key instruments in the neuronal orchestra. READ MORE

  6. 4. Non-linear synaptic integration on dendrites of striatal medium-spiny neuron : a computational study

    Author : Kai Du; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Striatum is the main input nucleus of basal ganglia. Medium-spiny neurons (MSNs), the principal neurons of the striatum, receive convergent excitatory inputs from cortex and thalamus, thus “gate” the information flow to the basal ganglia. READ MORE

  7. 5. Using Inhomogeneous Neuronal–Synaptic Dynamics for Spatiotemporal Pattern Recognition in Neuromorphic Processors

    Author : Mattias Nilsson; Fredrik Sandin; Foteini Liwicki; Jerker Delsing; Elisabetta Chicca; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cyber-Physical Systems; Cyberfysiska system;

    Abstract : Mixed-signal neuromorphic processors emulate the electrochemical dynamics of neurons and synapses using conventional analog CMOS-transistor technology and have potential for ultra-low-power machine learning and inference. However, the energy-efficiency of such systems is dependent on sparse, time-based information encoding and processing, and they are, furthermore, subject to imprecision from “device mismatch” in the analog circuitry. READ MORE