Search for dissertations about: "dengue thesis"

Showing result 11 - 15 of 26 swedish dissertations containing the words dengue thesis.

  2. 11. Functional characterization of interactions between the flavivirus NS5 protein and PDZ proteins of the mammalian host

    Author : Karin Ellencrona; Magnus Johansson; Andrew Davidson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus TBEV ; West-Nile virus WNV ; Dengue virus DENV ; flavivirus; PDZ domains; ZO-2; ZO-1; RIMS2; Scribble; Interferon; JAK-STAT signaling; PDZ array; virus-host protein interaction; Genetics; Genetik; molekylärgenetik; Molecular Genetics;

    Abstract : Flaviviruses are found all over the world and affect and infect millions of people every year. Flavivirus infection can lead to severe clinical outcomes resulting in neuronal damages e.g. Tick-borne encephalitis virus (TBEV), or severe hemorrhagic fevers e. READ MORE

  4. 12. An epidemiological and virological study on mosquito-borne flavivirus transmission : The role of urban livestock keeping and the risk for mosquito-borne zoonotic diseases in humans in Hanoi city, Vietnam

    Author : Thang Nguyen-Tien; Johanna Lindahl; Åke Lundkvist; Richard Paul; Uppsala universitet; []
    Keywords : urban flavivirus; mosquito-borne diseases; livestock keeping; urban Vietnam; Southeast Asia.; Medicinsk vetenskap; Medical Science;

    Abstract : Mosquito-borne diseases (MBDs), which are transmitted by the bite of mosquitoes to humans, are causing high morbidity and mortality worldwide and are emerging in many tropical cities. Urban livestock keeping is still growing in cities around the world, which can itself contribute to increasing the mosquito populations. READ MORE

  5. 13. Studies of Retroviral Reverse Transcriptase and Flaviviral Protease Enzymes as Antiviral Drug Targets : Applications in Antiviral Drug Discovery & Therapy

    Author : Muhammad Junaid; Jarl ES Wikberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virus; enzymes; HIV AIDS; retroviral reverse transcriptase; flaviviral protease; NRTIs; proteochemometrics; drug resistance; DEN; JEV; NS2B H -NS3pro; antiviral; drug targets; drug discovery; drug therapy.; Farmakologi; Pharmacology;

    Abstract : Viruses are a major threat to humans due to their unique adaptability, evolvability and  capability to control their hosts as parasites and genetic elements. HIV/AIDS is the third largest cause of death by infectious diseases in the world, and drug resistance due to the viral mutations is still the leading cause of treatment failure. READ MORE

  6. 14. Role of TGFβ-induced hyaluronan-CD44 signaling in cancer progression

    Author : Constantinos Kolliopoulos; Evi Heldin; Aristidis Moustakas; Jonathan Sleeman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hyaluronan; CD44; TGFβ; cancer; EMT; signal transduction; transcriptional regulation;

    Abstract : Hyaluronan, a prevalent glycosaminoglycan of the extracellular space often accumulates in pathological conditions, such as chronic inflammation, infection, and cancer. Hyaluronan synthase HAS2 has been responsible for the synthesis and deposition of hyaluronan in a variety of tumors. READ MORE

  7. 15. Decoding the language of transmission among vector-pathogen-host

    Author : Melika Hajkazemian; S. Noushin Emami; Richard Hopkins; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Vector-borne disease; Malaria; Anopheles; Plasmodium falciparum; Zika; Aedes; Vector control strategy; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Vector-borne diseases account for over 17 percent of all infectious diseases and lead to more than 700,000 mortalities annually. Importantly, there is a complex interaction between infectious organisms and their host. READ MORE