Search for dissertations about: "deoxycholic acid"

Showing result 1 - 5 of 10 swedish dissertations containing the words deoxycholic acid.

  2. 1. Paracellular permeability of intestinal epithelia.An in vivo study

    Author : Britt-Marie Fihn; Göteborgs universitet; []
    Keywords : paracellular permeability; intestinal epithelia; deoxycholic acid; cholera toxin; glucose absorption; water transport;

    Abstract : Aim: Investigate the importance of paracellular transport of water and solutes during physiological and pathophysiological conditions. Methods: The transport of small water-soluble inert permeability markers, was studied in jejunum and colon in anesthetized rats and cats during normal conditions and during exposure to cholera toxin (CT) and deoxycholic acid (DCA). READ MORE

  4. 2. On the regulation of hepatic cholesterol and bile acid metabolism in gallstone patients

    Author : Carl-Gustaf Hillebrant; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bile acid synthesis; biliary lipids; cholesterol synthesis; cholesterol 7a-hydroxylase; cholesterol synthesis inhibitor; chenodeoxycholic acid; cholestyramine; 7a-hydroxy-4-cholesten-3-one; HMG CoA reductase; lathosterol; lipoproteins; lithocholic acid; plasma apheresis; ursodeoxycholic acid;

    Abstract : The liver plays an important role in the regulation of cholesterol homeostasis, therefore also in the pathogenesis of arteriosclerosis and gallstone disease. The quantitatively most important way by which cholesterol is removed from the human body is via the bile, either as free cholesterol or after transformation to bile acids. READ MORE

  5. 3. Crohn's disease in Stockholm County : epidemiological panorama and associated gallstone disease

    Author : Annika Lapidus; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bile acid; biliary lipids; bilirubin; cholesterol; colon; Crohn s disease; epidemiology; gallstone; ileal resection; incidence; prevalence; prognosis.;

    Abstract : Crohn's disease is a chronic inflammatory bowel disease of obscure etiology, affecting any part of the gastrointestinal tract but the ileocaecal region in particular. The annual incidence has gradually been increasing, and the clinical pattern has changed; a shift towards colorectal involvement as well as an increasing number of elderly patients has been observed. READ MORE

  6. 4. The interplay between bile acids and gut microbiota in metabolic and hepatobiliary disease

    Author : Wilhelm Sjöland; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gut microbiota; bile acids; type 2 diabetes; hepatobiliary disease; obesity; metabolic disease;

    Abstract : The gut microbiota, a metabolic regulator, orchestrates the production of bioactive metabolites such as secondary bile acids. Growing evidence suggests that shifts in the gut microbiota composition are linked to metabolic and hepatobiliary disease. READ MORE

  7. 5. Collagenous colitis : The influence of inflammation and bile acids on intestinal barrier function

    Author : Andreas Münch; Magnus Ström; Johan Söderholm; Magnus Simrén; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Background and aims: Collagenous colitis (CC) is a diarrheal disorder with an incidence rate of 5-6/100000 inhabitants, affecting mainly middle-aged women. The diagnosis is made by histology of the colonic mucosa. Classical findings are a thickened subepithelial collagenous layer and chronic inflammation in the lamina propria. READ MORE