Search for dissertations about: "deoxyribonucleic acid"

Showing result 1 - 5 of 24 swedish dissertations containing the words deoxyribonucleic acid.

2. 1. Deoxyribonucleic acid metabolism in the small intestine in vivo and in vitro : A study of the normal and 180-MeV proton of 60 Co gamma irradiated mouse

   Author : Karl J. Johansson; Uppsala universitet; []
   Keywords : NATURAL SCIENCES; NATURVETENSKAP;

   Abstract : .... READ MORE

4. 2. Longitudinal studies of human papillomavirus infection : with special reference to screening for cervical cancer and treatment of CIN

   Author : Kristina Elfgren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Human papillomavirus; natural history; risk factors; Human immunodeficiency virus; antibodies; cervical intraepithelial neoplasia; cervical cancer screening; Human papillomavirus screening; treatment; clearance of Human papillomavirus deoxyribonucleic acid.;

   Abstract : Aim: To study the natural history of Human Papillomavirus (HPV) infection in the general population and among women with acquired immunosuppression as well as to evaluate possible uses of human papillomavirus testing in cervical screening programs. Study I: Women treated for cervical intraepithelial neoplasi (CIN) were analysed for presence of HPV DNA by PCR and for HPV antibodies by ELISA before and 16-27 months later. READ MORE

5. 3. Ultra-sensitive measurements of magnetically labelled RCA products in a microfluidic channel using a high-Tc SQUID

   Author : Sobhan Sepehri; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; diagnostics.; high-Tc SQUID; biosensor; magnetic nanoparticle; rolling circle amplification; magnetic bioassay;

   Abstract : The development of a nucleic acid (deoxyribonucleic acid (DNA), ribonucleic acid (RNA)) bioassay based on magnetic nanoparticles (MNPs) with a high-Tc superconducting quantum interference device (SQUID) gradiometer as a magnetic readout is described. The specific binding of the MNPs to the target DNA molecules changes the MNPs size distribution and, therefore, the relaxation dynamics and is measured by magnetic ac susceptometry. READ MORE

6. 4. Theoretical studies on photophysics and photochemistry of DNA

   Author : Yuejie Ai; Yi Luo; Lluís Blancafort; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Quantum chemistry; Kvantkemi; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Abstract : Theoretical studies on biological systems like nucleic acid and protein have been widely developed in the past 50 years and will continue to be a topic of interest in forefronts of natural science. In addition to experimental science, computational modeling can give useful information and help us to understand biochemical issues at molecular, atomic and even electronic levels. READ MORE

7. 5. Comparative genome and proteome analysis of brain tissue from MK-801-treated rats

   Author : Linda Paulson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Schizophrenia; MK-801; rat; animal model; proteomics; genomics;

   Abstract : Symptoms of intoxication with non-competitive N-methyl-D-aspartate (NMDA)-receptor antagonists, closely mimic symptoms in patients with schizophrenia, and therefore [+]-5-methyl-10,11-dihydro-5H-dibenzo-[a,d]-cycloheptene-5,10-iminehydrogen-maleate (MK-801, dizocilpine) treated rodents are often used as a model for schizophrenia. To investigate if administration of the NMDA receptor antagonist MK-801 to rats would induce messenger ribonucleic acid (mRNA) or protein disturbances mimicking those observed in schizophrenic patients, complementary deoxyribonucleic acid (cDNA) microarrays and two-dimensional gel-electrophoresis in combination with mass spectrometry were used, respectively. READ MORE