Search for dissertations about: "design PCR for diagnosis"

Showing result 1 - 5 of 9 swedish dissertations containing the words design PCR for diagnosis.

  1. 1. Detection and Quantification of Variable Viral RNA by Real-Time PCR Assays

    Author : Shaman Muradrasoli; Jonas Blomberg; Göran Friman; Maria Brytting; Uppsala universitet; []
    Keywords : Virology; Diagnosis of Viral RNA; QPCR; RNA virus; broadly targeted PCR; probe design strategy; Infectious diseases; Medicin; Medicine;

    Abstract : As the area of nucleic acid based technologies develops, so will our understanding of how structural variations in DNA and RNA pathogens are associated with disease. The overall goal of this thesis is the development of broadly targeted measurement techniques for variable viral RNA by Real-Time PCR (here referred to as quantitative reverse transcriptase PCR, QRT-PCR). READ MORE

  2. 2. Respiratory tract infections in primary care - aspects of diagnosis and treatment

    Author : Karin Rystedt; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Group A streptococci; Penicillin V; Phenoxymethylpenicillin; Rapid antigen detection test; Antimicrobial resistance; Faecal microbiota; C-reactive protein; Influenza-like illness; Influenza A; Primary care;

    Abstract : Background Primary health care is accountable for most of the antibiotic prescriptions in humans. In Sweden, most of these antibiotics are used for respiratory tract infections, and pharyngotonsillitis (acute sore throat) is the single respiratory tract infection that leads to most antibiotic prescriptions. READ MORE

  3. 3. Molecular endocrinology of target enzymes in androgen metabolism : implications for prostate cancer

    Author : Torbjörn Söderström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Genes that are responsible for variations in drug and hormonal responses are sometimes also associated with the pathophysiology of diseases. Understanding the aetiology of a disease is often essential for the design of effective drugs. Androgens are implicated in the development of prostate cancer and benign prostate hyperplasia (BPI]). READ MORE

  4. 4. Type-specific human papillomavirus antibodies : detection, characterization and application in seroepidemiology

    Author : Zhaohui Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : antagonism; antibody; capsids; cervical carcinoma; CIN; epidemiology; HPV; isotype; neutralizing epitope; PCR; STDs; trends over time; VLPs;

    Abstract : Background: Human Papillomavirus (HPV) is a sexually transmitted DNA virus that causes several human cancers, notably cervical and other anogenital cancers. The antibody response to this virus is of interest both because knowledge of the antigenic structures that induce protective immunity forms the basis for prophylactic vaccine development and because it forms the basis of seroepidemiology, the method of choice for studies of HPV infectivity, of HPV spread in populations and of cancer risks following HPV exposure. READ MORE

  5. 5. Liquid biopsies in pediatric oncology : towards clinical implementation

    Author : Cecilia Arthur; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : During the last few years, liquid biopsies based on cell-free DNA (cfDNA) have become approved for clinical use in several areas of adult oncology. Due to the minimally invasive nature of this procedure, liquid biopsies could serve many purposes in childhood oncology as well. READ MORE