Search for dissertations about: "design die"

Showing result 11 - 15 of 80 swedish dissertations containing the words design die.

  1. 11. Design and Synthesis of Malarial Aspartic Protease Inhibitors

    Author : Karolina Ersmark; Anders Hallberg; Michael Rowley; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; malaria; plasmepsin; aspartic protease; protease inhibitor; macrocycle; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Abstract : Malaria is one of the major public health problems in the world. Approximately 500 million people are afflicted and almost 3 million people die from the disease each year. Of the four causative species Plasmodium falciparum is the most lethal. READ MORE

  2. 12. On determining lost core viability in high-pressure die casting using Computational Continuum Mechanics

    Author : Sebastian Kohlstädt; Pär Jönsson; Julio Hernandez; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high-pressure die casting; lost salt cores; computational continuum mechanics; two-phase compressible flow; OpenFOAM; CFD; fluid-structure interaction; volume-of-fluid method;

    Abstract : The subject of this thesis work is to investigate whether Computational ContinuumMechanics (CCM) can serve as a valuable tool for the casting engineerto determine a priori whether a housing concept with inlying geometries thatso far only exists in Computer Aided Design (CAD) will have the desired coolingperformance and will be manufacturable with an acceptable number ofrejects.As of spring 2019, no application in serial production of lost cores, i. READ MORE

  3. 13. Hit Identification and Hit Expansion in Antituberculosis Drug Discovery : Design and Synthesis of Glutamine Synthetase and 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitors

    Author : Anneli Nordqvist; Anders Karlén; Mats Larhed; Anders Hallberg; Anna Linusson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tuberculosis; Glutamine synthetase; Imidazo[1; 2-a]pyridine analogues; Focused hierarchical design of experiments; DXR; Fosmidomycin analogues; 1-Deoxy-D-xylulose-5-phosphate reductoisomerase; Cinnamaldehydes; Oxidative Heck reaction; Pharmaceutical chemistry; Läkemedelskemi; Medicinal Chemistry; Läkemedelskemi;

    Abstract : Since the discovery of Mycobacterium tuberculosis (Mtb) as the bacterial agent causing tuberculosis, the permanent eradication of this disease has proven challenging. Although a number of drugs exist for the treatment of tuberculosis, 1.7 million people still die every year from this infection. READ MORE

  4. 14. Design Aspects of Fully Integrated Multiband Multistandard Front-End Receivers

    Author : Adiseno; KTH; []
    Keywords : low-noise amplifier; mixer; RF front-end; wireless receiver; noise figure; linearity; bandwidth; dual-loop feedback;

    Abstract : In this thesis, design aspects of fully integrated multibandmultistandard front-end receivers are investigated based onthree fundamental aspects: noise, linearity and operatingfrequency. System level studies were carried out to investigatethe effects of different modulation techniques, duplexing andmultiple access methods on the noise, linearity and selectivityperformance of the circuit. READ MORE

  5. 15. Integrated Community Energy Systems

    Author : Binod Prasad Koirala; Mehrdad Ghandari; Rudi A. Hakvoort; Reinier Van der Veen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Distributed energy resources; community energy; local energy systems; institutional design; smart grids; energy system integration; community engagement; Energy Technology; Energiteknik; Electrical Engineering; Elektro- och systemteknik;

    Abstract : Energy systems across the globe are going through a radical transformation as a result of technological and institutional changes, depletion of fossil fuel resources, and climate change. Accordingly, local energy initiatives are emerging and increasing number of the business models are focusing on the end-users. READ MORE