Search for dissertations about: "detargeting"

Found 1 swedish dissertation containing the word detargeting.

2. 1. Retargeting of adenovirus vectors. Viral ligands and cellular receptors

   Author : Petra Henning; Göteborgs universitet; []
   Keywords : Adenovirus; vector; gene therapy; gene transfer; retargeting; detargeting; tumor targeting; fiber; pIX; affibody molecule; single chain antibody;

   Abstract : Gene therapy is one of the newest technologies attempted to treat human cancer. Progress in the field has however been hampered by the lack of efficient and safe vectors. Ideal vectors should specifically transduce desired cells in vivo. This thesis is devoted to the development and evaluation of retargeted adenovirus type 5 (Ad5) vectors. READ MORE