Search for dissertations about: "detection of virulence factors"

Showing result 1 - 5 of 27 swedish dissertations containing the words detection of virulence factors.

  2. 1. Studies of the pathogenesis of Enterohemorrhagic Escherichia coli infections: pathogen virulence factors and host response

    Author : Carla Calderon Toledo; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; host-pathogen; MyD88; TLRs; LEE; Shiga toxin; HUS; EHEC; EPEC; immune response; virulence factors;

    Abstract : Enterohemorrhagic Escherichia coli (EHEC) is a highly virulent pathogen that can cause diarrhea and a life-threatening disease known as hemolytic uremic syndrome. EHEC possess an array of virulence factors that can exert severe consequences in the host. Shiga toxin constitutes a key virulence factor. READ MORE

  4. 2. Survival of infectious agents and detection of their resistance and virulence factors

    Author : Eva Tano; Åsa Melhus; Jan Sjölin; Marie-Louise Danielsson-Tham; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transportation system; swab; polymicrobial samples; Neisseria gonorrhoeae; bacteremia; exotoxins; Staphylococcus aureus; TSST-1; silver; silver resistance; wound dressing; sil genes; laundry; tumble drying; bacterial decontamination;

    Abstract : In the first study, three different transport systems for bacteria were evaluated. The CLSI M40-A guideline was used to monitor the maintenance of both mono- and polymicrobial samples during a simulated transportation at room temperature that lasted 0-48 h. READ MORE

  5. 3. Virulence factors and clonal relatedness of enterotoxigenic Escherichia coli (ETEC) isolated from children with diarrhoea in Bolivia

    Author : Claudia Rodas Miranda; Göteborgs universitet; []
    Keywords : Enterotoxigenic Escherichia coli; Virulence factors; Bolivia; Children; Severity of disease; Relatedness;

    Abstract : Enterotoxigenic Escherichia coli (ETEC) is one of the major causes of diarrhoea in children under five years of age in developing countries and in travellers to these settings. To cause disease, ETEC must be able to colonize the small intestine and produce heat-stable enterotoxin (ST) or heat-labile toxin (LT) or both toxins. READ MORE

  6. 4. Real-time PCR for diagnosis of botulism and quantification of neurotoxin gene expression in Clostridium botulinum

    Author : Ingrid Artin; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; detection; qRT-PCR; Clostridium botulinum; molecular methods;

    Abstract : The objectives of the work presented in this thesis have been to develop molecular methods for (i) detection of Clostridium botulinum in food and clinical samples, and (ii) monitoring the expression of the neurotoxin gene, cnt, during different growth phases and under different growth conditions. For the diagnosis of botulism, a real-time PCR-based method including an internal amplification control for C. READ MORE

  7. 5. Enterococci in Swedish intensive care units : studies on epidemiology, mechanisms of antibiotic resistance and virulence factors

    Author : Anita Hällgren; Arnfinn Sundsfjord; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The purpose of this thesis was to study enterococci in Sweden, their resistance to antibiotics in general and high-level gentamicin resistance (HLGR) in particular, with a special focus on the ICU setting. Dynamics of rectal colonisation during prolonged intensive care unit (ICU) stay was assessed. READ MORE