Search for dissertations about: "dethiobiotin synthetase"

Found 1 swedish dissertation containing the words dethiobiotin synthetase.

2. 1. Enzymatic mechanisms in biotin synthesis : vitamin B6 catalysis and phosphoryl transfer

   Author : Jenny Sandmark; Karolinska Institutet; Karolinska Institutet; []
   Keywords : X-ray crystallography; biotin biosynthesis; pyridoxal-5 -phosphate; aminotransferase; aluminium fluoride; S-adenosyl-L-methionine; 7; 8-diaminopelargonic acid synthase; dethiobiotin synthetase; biotin; phosphoryl transfer; amiclenomycin.;

   Abstract : With the large number of pathogenic bacteria that have developed antibiotic resistance it is increasingly important to find new targets for antibiotics. Our interest in the biotin biosynthesis pathway originates from this drug design perspective. All organisms require biotin, but it is only synthesised in bacteria, in plants and in some fungi. READ MORE