Search for dissertations about: "developing brain"

Showing result 1 - 5 of 312 swedish dissertations containing the words developing brain.

  2. 1. Developing brain and systemic inflammation: a "Toll-like" link with consequences

    Author : Amin Mottahedin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; developing brain; neonatal brain injury; hypoxia-ischemia; inflammation; infection; Toll-like receptor; choroid plexus; neuroimmunology; Mitochondria;

    Abstract : The developing brain is vulnerable to external insults, and perinatal brain injury (PBI) is a major cause of life-long neurological syndromes such as cerebral palsy. Currently, no pharmaceutical intervention is available. Hypoxia/ischemia (HI), infections and inflammation are implicated in the pathogenesis of PBI. READ MORE

  4. 2. Diving and the brain

    Author : Anders Rosén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomarkers; brain; central nervous system; decompression sickness; dive research; diving; neuronal damage; saturation diving; tau protein; venous gas embolism; neurofilament light; glial fibrillary acid protein; tau; VGE;

    Abstract : Abstract Introduction There are reports that long-term diving is associated with cognitive impairments. This raises the question if diving itself is harmful to the brain in the absence of decompression sickness or hypoxia. READ MORE

  5. 3. Caspase-dependent and caspase-independent neuronal injury in the developing brain

    Author : Changlian Zhu; Göteborgs universitet; []
    Keywords : hypoxia ischemia; neonatal; cell death; caspase; apoptosis-inducing factor; brain; apoptosis; autophagy; nitric oxide;

    Abstract : Aims: To investigate the mechanisms of neuronal cell death after hypoxia-ischemia in the developing brain.Methods: Rats or mice were subjected to left common carotid artery ligation plus hypoxia. Animals were sacrificed at certain time points after hypoxia-ischemia. READ MORE

  6. 4. Protection of the developing brain with trophic factors. Signaling through serine/threonine kinase pathways

    Author : Katarina Gustafson Brywe; Göteborgs universitet; []
    Keywords : hypoxia-ischemia; neonatal; brain; growth factors; ser thr kinases;

    Abstract : Background: Perinatal asphyxia still constitutes a clinical hazard associated withconsiderable neurologic morbidity. There is today no therapy in clinical use toprotect the brain after such insult. READ MORE

  7. 5. Gut microbes and the developing brain

    Author : Tim Arentsen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The discovery that commensal gut microbiota can influence host development and physiology beyond the gastrointestinal (GI) tract has triggered a paradigm shift in our conceptualization of the origin of human diseases. A growing body of preclinical research has demonstrated that gut microbiota exert a modulatory role on the development and function of brain circuits involved in motor control, emotion and cognition. READ MORE