Search for dissertations about: "development of digital libraries"

Showing result 1 - 5 of 12 swedish dissertations containing the words development of digital libraries.

  1. 1. How reproductive is a reproduction? : Digital transmission of text-based documents

    University dissertation from Borås : Högskolan i Borås

    Author : Lars Björk; Högskolan i Borås.; [2015]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Boundary objects; Cultural heritage; Digital humanities; Digital transmission; Digitisation; Document studies; Libraries; Materiality; Media theory; Library and Information Science; Biblioteks- och informationsvetenskap;

    Abstract : Heritage institutions today increasingly rely on digital formats for access, use and re-useof their collections. Books and other text-based documents, previously accessed on locationin libraries are now transferred into digital format and managed, distributed, andengaged as binary encoded representations. READ MORE

  2. 2. Development and Application of Computational Methods in Antitubercular Drug Design Identification of Novel Inhibitors of Ribonucleotide Reductase

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Daniel Muthas; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY Pharmaceutical chemistry; FARMACI Farmaceutisk kemi; Medicinal Chemistry; läkemedelskemi;

    Abstract : Tuberculosis kills approximately 1.7 million people each year around the world making it one of the most lethal infectious diseases. This thesis concerns the development of two computational tools that can support the early stages of drug discovery, and their use in an anti-tubercular drug discovery program. READ MORE

  3. 3. Making Sense of Antisense

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Johan Reimegård; Uppsala universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; sRNA; miRNA; RNA; target prediction; SOLiD siRNA; E.coli; D.discoideum; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi; Bioinformatik; Bioinformatics; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : RNA is a highly versatile molecule with functions that span from being a messenger in the transfer from DNA to protein, a catalytic molecule important for key processes in the cell to a regulator of gene expression. The post-genomic era and the use of new techniques to sequence RNAs have dramatically increased the number of regulatory RNAs during the last decade. READ MORE

  4. 4. Sensitivity, Noise and Detection of Enzyme Inhibition in Progress Curves

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Omar Gutierrez Arenas; Uppsala universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Progress curves; limit of detection; Z -factor; primary screening; enzyme inhibition; error structure; sensitivity analysis; High-throughput screning; Biokemi;

    Abstract : Starting with the development of an enzymatic assay, where an enzyme in solution hydrolysed a solid-phase bound peptide, a model for the kinetics of enzyme action was introduced. This model allowed the estimation of kinetic parameters and enzyme activity for a system that has the peculiarity of not being saturable with the substrate, but with the enzyme. READ MORE

  5. 5. Advances for Biomarker Discovery in Neuroproteomics using Mass Spectrometry From Method Development to Clinical Application

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marcus O.D. Sjödin; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Biomarker; Proteomics; Central Nervous System; Cerebrospinal Fluid; Traumatic Brain Injury; Cloud-Point Extraction; Neuroproteomics; Relative Quantification; Spinal Cord Stimulation; Neuropathic Pain; Analytical Chemistry; Analytisk kemi;

    Abstract : Proteins offer a prominent group of compounds which may be ubiquitously affected in disease and used as biomarkers for early diagnosis, assessing treatment or drug development. Clinical proteomics aim to screen for protein biomarkers by a comprehensive analysis of all proteins expressed in a biological matrix during a certain pathology. READ MORE