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Showing result 1 - 5 of 95 swedish dissertations matching the above criteria.

  2. 1. Epigenetic Regulation of the H19 Chromatin Insulator in Development and Disease

    Author : Claes Holmgren; Rolf Ohlsson; Tomas Ekstöm; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Developmental Biology; Miljömedicinsk utvecklingsbiologi;

    Abstract : The coordinated regulation of gene expression must be tightly controlled for normal development to occur. In mammals, this issue is further complicated by the requirement of both the maternal and paternal genomes for normal development, reflecting the fact that a subset of genes are monoallelically expressed depending on parental inheritance, a phenomenon known as genomic imprinting. READ MORE

  4. 2. Chromatin Insulators and CTCF: Architects of Epigenetic States during Development

    Author : Rituparna Mukhopadhyay; Rolf Ohlsson; Karim Malik; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; DNA methylation; CTCF; Chromatin insulators; Microarray; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Abstract : A controlled and efficient coordination of gene expression is the key for normal development of an organism. In mammals, a subset of autosomal genes is expressed monoallelically depending on the sex of the transmitting parent, a phenomenon known as genomic imprinting. READ MORE

  5. 3. Selection and Floral Evolution in Platanthera bifolia and P. chlorantha (Orchidaceae)

    Author : Johanne Maad; Charles B. Fenster; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Evolution; phenotypic selection; male function hypothesis; mating systems; floral shifts; orchids; pollination; moth pollinators; Platanthera.; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; systematisk botanik; Systematic Botany;

    Abstract : Natural selection mediated by pollinators has influenced the evolution of floral diversity of the flowering plants (angiosperms). The scope of this thesis was to study: 1) phenotypic selection, 2) mating systems, and 3) floral shifts involved in plant speciation. Model plant species were Platanthera bifolia and P. chlorantha (Orchidaceae). READ MORE

  6. 4. The Epigenetics of Gene Transcription and Higher Order Chromatin Conformation

    Author : Vijay Kumar Tiwari; Rolf Ohlsson; Terumi Kohwi-Shigematsu; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; DNA-protein interactions; Nuclear organization; Transcriptional regulation; Higher order chromatin conformations; Epigenetic reprogramming; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Abstract : It is becoming increasingly clear that long-range control of gene expression is mediated through direct physical interactions between genes and regulatory elements, either intra- or interchromosomally. In addition to transcriptional initiation, formation of active chromatin hubs seem to be crucial for increased transcriptional efficiency as well as insulation from neighbouring heterochromatic environment. READ MORE

  7. 5. Trade-off between starvation and predation : Weight-watching in Yellowhammers

    Author : Ineke T. van der Veen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; populationsbiologi; Population Biology;

    Abstract : In this thesis I show that captive yellowhammers (Emberiza citrinella) strategically adjusted their level of body mass and diurnal trajectory of mass increase to experimentally increased predation risk. During winter, small birds need large fat reserves to survive the night. Therefore, they build up fat reserves every day. READ MORE