Search for dissertations about: "dexamethasone"

Showing result 21 - 25 of 132 swedish dissertations containing the word dexamethasone.

  2. 21. Obstructive sleep apnea syndrome. Treatment outcome, psychiatric aspects, neuropsychology and quality of life

    Author : Pia Dahlöf; Göteborgs universitet; []
    Keywords : obstructive sleep apnea syndrome; uvulopalatopharyngoplasty; oxygen desaturation index; psychiatric morbidity; depression; dexamethasone suppression test; verbal learning and recall; executive functions; quality of life; spouses; long-term follow-up;

    Abstract : Background: Obstructive sleep apnea syndrome (OSAS) is characterized by snoring and apneas during sleep leading to oxygen desaturation, sleep fragmentation and excessive daytime sleepiness. Prior reports have indicated that psychiatric morbidity associated with sleep apnea might be reversed by intervention correcting the sleep related breathing disorder. READ MORE

  4. 22. Long-term follow-up of prenatally dexamethasone-treated children at risk for congenital adrenal hyperplasia

    Author : Tatja Hirvikoski; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Congenital adrenal hyperplasia (CAH) is a disorder of steroid genesis affecting approximately 1:10 000 children and leading to increased levels of androgens during foetal life and subsequent virilization of external genitalia in affected girls. However, prenatal virilization can be eliminated by antenatal dexamethasone (DEX) treatment. READ MORE

  5. 23. The role of apoptosis in growth plate cartilage during normal and abnormal growth

    Author : Dionisios Chrysis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Apoptosis; growth plate; dexamethasone; cytokines;

    Abstract : Longitudinal bone growth occurs at the growth plate where resting chondrocytes proliferate, differentiate into a hypertrophic form, and finally become terminal hypertrophic chondrocytes before giving rise to bone. Because growth occurs when proliferation exceeds cell death, alterations in cell death by apoptosis, which is essential for the maintenance of tissue homeostasis, could affect growth. READ MORE

  6. 24. Novel mechanisms of glucocorticoid-induced insulin resistance in human adipose tissue

    Author : Cherno Omar Sidibeh; Jan Eriksson; Maria João Pereira; Anna Krook; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cannabinoid receptor type 1 fkbp51 dexamethasone type 2 diabetes adipocytes; Medicinsk vetenskap; Medical Science;

    Abstract : The global prevalence of obesity and type 2 diabetes (T2D) is increasing. From a public health perspective, it is therefore of interest to identify common underlying mechanisms of these comorbidities. Glucocorticoids are steroid hormones that are important in stress regulation in mammals. READ MORE

  7. 25. Oxidative stress and proteolysis in the lens. Effects of anti-inflammatory drugs

    Author : Anne Kling-Petersen; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oxidation NSAIDs ASA dexamethasone apoptosis GSH GSSG proteasome lens epithelial cells mouse lens cataract;

    Abstract : Oxidative stress has been implied in formation of age-related cataract. The objectives of this thesis were to study redox regulation of proteolysis and oxidative/antioxidative effects of anti-inflammatory substances in human lens epithelial cells (HLEC) and intact mouse lenses. READ MORE