Search for dissertations about: "diabetes atherosclerosis"

Showing result 1 - 5 of 124 swedish dissertations containing the words diabetes atherosclerosis.

  2. 1. NFAT signaling in chronic and acute inflammation - A novel target for the treatment of diabetic vascular complications and acute pancreatitis?

    Author : Anna Zetterqvist; Diabetiska komplikationer; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NFAT; vascular; diabetes; inflammation; atherosclerosis; diabetic retinopathy; acute pancreatitis; osteopontin; VCAM-1; A-285222;

    Abstract : Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. READ MORE

  4. 2. Early arterial disease of the lower extremities in diabetes : diagnostic evaluation and risk markers

    Author : David Sahli; Maria Svensson; Eric Wahlberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes mellitus; ankle blood pressure; toe blood pressure; screening; risk markers; mediasclerosis; macroangiopathy; fibrinolysis; inflammation; MEDICINE; MEDICIN; Diabetology; Diabetologi;

    Abstract : The aim of the present thesis was to assess the occurrence of early lower extremity arterial disease (LEAD) in patients with diabetes and to assess novel potential risk markers for development or worsening of LEAD in the same patients. In parallel different measures of impaired peripheral circulation were evaluated. READ MORE

  5. 3. Sugar-Coated. The role of sugar intake and cardiovascular disease development in the context of nutritional recommendations

    Author : Esther González-Padilla; Nutritionsepidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sugar intake; Added sugar; Free sugar; Sugar-sweetened beverages; Nutritional recommendations; Micronutrient dilution; Cardiovascular disease; Atherosclerosis; Intima media thickness IMT ; Stroke; Swedish dietary guidelines; Mediterranean diet; Genetics; FGF21 gene; Nutritional epidemiology;

    Abstract : .... READ MORE

  6. 4. Epigenetic Mapping in Type 2 Diabetes. Glucose-triggered histone modifications in various tissues

    Author : Bompada Pradeep; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; epigenetics; histone modifications; genome editing; ChIP-seq; RNA-seq; pancreatic islets; diabetic kidney disease; peripheral blood mononuclear cells; atherosclerosis;

    Abstract : Epigenetic modifications triggered by high glucose may predispose to diabetes risk by regulating gene expression activity. A growing body of evidence suggests that histone modification which is an essential component of epigenetic mechanism may play an important role in the development of type 2 diabetes (T2D) and its complications. READ MORE

  7. 5. Studies on receptors for modified LDL in human monocytes and macrophages : a link between diabetes and atherosclerosis?

    Author : Linda Svensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; diabetes CD14; CD36; CD64; fatty acid; flow cytometry; macrophage; monocyte; scavenger receptor;

    Abstract : Type 2 diabetes increases the risk for cardiovascular disease three- to fourfold. Because of the rise in diabetes prevalence there is a need for a better understanding of the link between diabetes and atherosclerosis. READ MORE