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Showing result 1 - 5 of 105 swedish dissertations matching the above criteria.

  2. 1. On Meal Effects and DPP-4 Inhibition Islet- and Incretin Hormones in Health and Type 2 Diabetes

    Author : Wathik Alsalim; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; Healthy subjects; Meal composition; Incretin hormones; DPP-4 inhibition;

    Abstract : .... READ MORE

  4. 2. Pathophysiology and treatment of defective insulin secretion in diabetes

    Author : Anders Rosengren; Diabetes - öpatofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic beta-cells; stem cells; genetics; exocytosis; Adra2a; PACAP; GLP-1; Physiology; Fysiologi; secreting systems; Endocrinology; diabetology; Endokrinologi; insulin secretion; Diabetes mellitus; sekretion; diabetologi;

    Abstract : Defective insulin secretion is a central feature in diabetes mellitus and results from reduced pancreatic beta-cell mass as well as aberrant beta-cell function. The pathophysiology of diabetes is incompletely known, but a strong hereditary component is suggested. READ MORE

  5. 3. Trials of Diets for Treatment of Diabetes : A comparison of diets for treatment of type 2 diabetes, aspects on long and short term effects

    Author : Hans Guldbrand; Fredrik Nyström; Carl Johan Östgren; Staffan Lindeberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dietary intervention; type 2 diabetes; low-carbohydrate diet; blood glucose; blood lipids; insulin; body mass index; quality of life; inflammation; cytokine;

    Abstract : BackgroundType 2 diabetes is a common disease and the prevalence has increased in large parts of the world. In treatment of diabetes the type of diet is of great importance considering metabolic factors such as glucose level and blood lipids. READ MORE

  6. 4. Physiology and Pathophysiology of Hormone Secretion from lslets of Langerhans

    Author : Samuel Acreman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet; diabetes; glucagon; insulin; somatostatin; incretin; pancreas; hypoglycaemia; tetraspanin; GLP-1; endoplasmic reticulum;

    Abstract : Diabetes is a metabolic disorder stemming from the improper regulation of blood glucose levels by hormones secreted by pancreatic islets of Langerhans. Paper I describes the mechanism by which glucose can regulate glucagon secretion, independent of membrane potential, from pancreatic α-cells, via modulation of endoplasmic reticulum Ca2+ handling. READ MORE

  7. 5. Mechanisms of insulin exocytosis and release

    Author : Sebastian Barg; Islet cell physiology; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ClC-3; electrophyiology; confocal microscopy; calcium channel; readily releasable pool; exocytosis; insulin; diabetes; green fluorescent protein; Physiology; Fysiologi;

    Abstract : Endocrine cells as well as neurons release their hormones and transmitters by regulated exocytosis. In the pancreatic B-cell, stimuli like glucose initiate biochemical and electrical processes that culminate in influx of Ca2+, which then triggers exocytosis of insulin-containing granules. READ MORE