Search for dissertations about: "diabetes hormones"

Showing result 6 - 10 of 105 swedish dissertations containing the words diabetes hormones.

  2. 6. Immunomodulatory properties of steroid hormones

    Author : Maria Taube; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DTH; oestradiol; corticosteroids; T cells; SCID mice; adoptive transfer; thymus; spleen.;

    Abstract : Recent epidemiological, clinical and experimental evidence have suggested that steroid hormones play an important role in immune responses and in immune-mediated diseases. Many autoimmune diseases are treated with corticosteroids. READ MORE

  4. 7. The Human Pancreatic Islet Methylome and Its Role in Type 2 Diabetes

    Author : Tasnim Dayeh; Diabetes - epigenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CpG-SNP; glucagon secretion; insulin secretion; human pancreatic islets; DNA methylation; Epigenetics;

    Abstract : Islet dysfunction is central to the development and progression of type 2 diabetes (T2D). Epigenetic modifications are essential for establishing and maintaining cell identity and function in normal circumstances. Exposure to adverse environmental factors may alter the epigenome, and result in changes of gene expression and the resulting phenotype. READ MORE

  5. 8. Behavioral effects of female sex steroid hormones : models of PMS and PMDD in Wistar rats

    Author : Magnus Löfgren; Torbjörn Bäckström; Inga-Maj Johansson; Per Södersten; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PMS; PMDD; rats; progesterone; estradiol; behavior; individual response; stress interaction; tolerance; withdrawal; learning and memory; anxiety.; Biological research on drug dependence; Biologisk beroendeforskning; Endocrinology; Endokrinologi; Obstetrics and gynaecology; Obstetrik och gynekologi; Pharmacological research; Farmakologisk forskning; Obstetrics and gynaecology; Obstetrik och gynekologi; Psychology; Psykologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). READ MORE

  6. 9. Characterizing the pancreatic "isletome" : 3D optical imaging to study diabetes

    Author : Max Hahn; Ulf Ahlgren; András Gorzsás; Leif Carlsson; Alvin C. Powers; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D imaging; fluorescence microscopy; 3D image analysis; technique development; diabetes; Islet of Langerhans; Insulin; β-cell mass; pancreas; anatomy; molecular medicine medical sciences ; molekylär medicin medicinska vetenskaper ; medicinsk biokemi; Medical Biochemistry;

    Abstract : The pancreas is a specialised multipurpose organ, that can be separated into two major compartments: endocrine and exocrine. The exocrine part makes up the majority of the organ volume and functions to secrete digestive enzymes into the small intestine. READ MORE

  7. 10. Inhibition of 11 ß-HSD. Hemodynamic and hormonal response induced by liquorice

    Author : Helga A Sigurjónsdóttir; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11 ß-hydroxysteroid dehydrogenase; glycyrrhetinic acid; liquorice; hypertension; gender; androgen hormones;

    Abstract : Introduction: The enzyme 11 ß-hydroxysteroid-dehydrogenas (11 ß-HSD) type 2 that converts the active hormone cortisol to the inactive cortisone is inhibited by glycyrrhetinic acid (GA), the active substance in liquorice. This leads to hypertension, hypokalaemia and sodium- and fluid retention, the syndrome of pseudo-hyperaldosteronism. READ MORE