Search for dissertations about: "diabetes type 1 2012"

Showing result 11 - 15 of 59 swedish dissertations containing the words diabetes type 1 2012.

  2. 11. GAD65 An Immunomodulator in Type 1 Diabetes

    Author : Stina Axelsson; Rosaura Casas; Johnny Ludvigsson; Guro Gafvelin; Linköpings universitet; []
    Keywords : ;

    Abstract : Type 1 diabetes (T1D) is caused by a deficiency of insulin as a result of an autoimmune destruction of the pancreatic ² -cells. A possibility to preserve remaining ² -cells in children with newly diagnosed T1D is of great importance since sustained ² -cell function is recognized to result in reduced end-organ complications. READ MORE

  4. 12. Multiplex HLA-DR-DQ genotyping : for genetic epidemiology and clinical risk assessment

    Author : Ewa Lavant; Malmö högskola; []
    Keywords : HLA-DRB1; HLA-DQB1; HLA-DQA1; PCR-SSP; type 1 diabetes; celiac disease; autoimmune disease; capillary gel electrophoresis; genotyping;

    Abstract : The human leukocyte antigens (HLA) are highly polymorphic cell surface proteins encoded in the major histocompatibility complex (MHC) region on chromosome 6. The HLA system has been well known as transplantation antigens but the primary biological role of the HLA molecules is regulation of immune response by presenting peptide fragments to T-lymphocytes. READ MORE

  5. 13. Acute, ambulatory and central blood pressure measurements in diabetes

    Author : Magnus Wijkman; Fredrik Nyström; Carl Johan Östgren; Toste Länne; Jan Östergren; Linköpings universitet; []
    Keywords : Ambulatory blood pressure; Arterial stiffness; Central blood pressure; Diabetes; Hypertension.;

    Abstract : Background: In patients with diabetes, high blood pressure is an established risk factor for cardiovascular disease. The aim of this thesis was to explore the associations between blood pressure levels measured with different techniques and during different circumstances, and the degree of cardiovascular organ damage and subsequent prognosis in patients with diabetes. READ MORE

  6. 14. Genetic analysis of candidate susceptibility genes for type 1 diabetes

    Author : Samina Asad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Type 1 diabetes (T1D) is a complex disease where the pancreatic β-cells are destroyed in an autoimmune attack. For the patients, this leads to lifelong daily insulin treatment and increased risk for various kinds of complications. It is thought that both environmental as well as genetic factors act in concert to cause T1D. READ MORE

  7. 15. Nutritional and dysmetabolic factors with potential impact on type 2 diabetes : epidemiological and molecular studies

    Author : Tina Wirström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Type 2 Diabetes;

    Abstract : Diabetes is a group of diseases characterized by hyperglycaemia. Type 2 diabetes encompasses 85-95% of all diabetes with a prevalence that is expected to increase worldwide. READ MORE