Search for dissertations about: "diabetes type 1 2012"
Showing result 21 - 25 of 59 swedish dissertations containing the words diabetes type 1 2012.
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21. Aspects of Abnormal Glucose Regulation in Various Manifestations of Coronary Artery Disease
Abstract : Background Diabetes is common among patients with coronary artery disease (CAD) and is associated with an approximate doubling of the mortality risk in this patient population. Prediabetes, an intermediate glycometabolic state between normal and diabetic glucose homeostasis, is also prevalent in patients with CAD but its prognostic impact has not been studied in detail. READ MORE
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22. Diabetes and peripheral arterial disease
Abstract : Background: Diabetes mellitus increases the risk for peripheral arterial disease (PAD) early in life and the disease is likely to progress to advanced stages. Mechanisms responsible for premature PAD in diabetes are partly unknown. READ MORE
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23. Clinical aspects on glucose-lowering therapies in type 2 diabetes
Abstract : Type 2 diabetes is a progressive disease with deterioration of glycaemic control over time in association with loss of endogenous insulin secretion. As a consequence of this, sulphonylureas (SU), which exert their mode of action by stimulating the pancreatic β-cells, are expected to be less effective with longer duration of diabetes. READ MORE
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24. Metabolic variation in autoimmune diseases
Abstract : The human being and other animals contain immensely complex biochemical processes that govern their function on a cellular level. It is estimated that several thousand small molecules (metabolites) are produced by various biochemical pathways in humans. READ MORE
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25. The impact of glucotoxicity on pancreatic β-cell function
Abstract : Type 2 diabetes mellitus is connected with elevated plasma glucose levels which negatively influence β-cells and cause impaired glucose-stimulated insulin secretion (GSIS). The aim of present thesis was to investigate the impact of long-term hyperglycemia on the pancreatic islet β-cell function. READ MORE