Search for dissertations about: "diabetes type 1 puberty"
Showing result 1 - 5 of 8 swedish dissertations containing the words diabetes type 1 puberty.
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1. Exploring the Grey Zone between Type 1 and Type 2 Diabetes
Abstract : T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA), with age at onset after 35 years and non-insulin requiring at least for 6 month after diagnosis. READ MORE
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2. Genetic Loci Contributing to Spontaneous Autoimmune Diabetes
Abstract : Background and Aims: Spontaneous type 1 diabetes (T1D) in the BioBreeding (BB) rat mimics human T1D as the rats experience weight loss, polydipsia, polyuria, ketoacidosis, onset during puberty and insulin-dependency within a day after diagnosis. Because the DP rat develops T1D spontaneously, it is a prime laboratory animal for dissecting the genetics of T1D susceptibility without the need for external manipulation. READ MORE
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3. Body Composition in Adolescents with Type 1 Diabetes : Aspects of Glycaemic Control and Insulin Sensitivity
Abstract : Excessive weight gain has frequently been reported in adolescents with type 1 diabetes, especially in girls. In general, puberty is associated with reduced insulin sensitivity that is further diminished by overweight. The causes and consequences of excessive weight gain in adolescents with type 1 diabetes are not fully understood. READ MORE
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4. Diabetes and puberty : studies on hormonal factors of importance to the blood glucose control
Abstract : It is well known that, in children with type 1 diabetes, metabolic control often deteriorates during puberty. Better understanding of the mechanisms that cause deterioration of blood glucose control can lead to improved therapeutic approaches. READ MORE
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5. Long-acting insulin analogs in type 1 diabetes : effects on metabolic control, endogenous insulin production and the GH-IGF-axis
Abstract : The treatment goal in type 1 diabetes is to achieve near-normal glycemia. Despite of the advancements of subcutaneous insulin therapy and glucose monitoring, metabolic control is not fully normalized and secondary endocrine disturbances in the growth-hormone (GH) - Insulin-like Growth Factor (IGF)-axis are important for the deterioration of metabolic control, particularly in children at puberty. READ MORE