Search for dissertations about: "diabetology"

Showing result 31 - 35 of 102 swedish dissertations containing the word diabetology.

  2. 31. THE ROLE OF PHOSPHODIESTERASE 3B IN CAMP-MEDIATED REGULATION OF INSULIN SECRETION

    Author : Helena Jones; Signaltransduktionsforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cAMP; PDE3B; exocytosis; insulin; diabetes; Medicine human and vertebrates ; Medicin människa och djur ; diabetologi; sekretion; Endokrinologi; diabetology; Endocrinology; secreting systems;

    Abstract : Type 2 diabetes mellitus (T2DM) is characterized by various combinations of ?-cell failure and insulin resistance leading to hyperglycemia and glucose intolerance. In order to maintain glucose tolerance in the insulin resistance state, increased insulin secretion is a requirement and it is because of inadequate islet adaptation that glucose intolerance develops in T2DM. READ MORE

  4. 32. The Importance of CTLA-4 and HLA Class II for Type 1 Diabetes Immunology

    Author : Carl-Oscar Jonson; Johnny Ludvigsson; Maria Faresjö; Dan Holmberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; Genetics; Diabetology; Diabetologi;

    Abstract : Type 1 Diabetes (T1D) is a serious chronic disease that results from an autoimmune destruction of the insulin-producing beta cells. Sweden has the second highest incidence of T1D in the world, and it affects more and more children each year. Genes controlling key functions of the immune system regulation of autoimmunity has been associated to T1D. READ MORE

  5. 33. On the pharmacodynamics, pharmacokinetics and metabolism of sulphonylurea and its metabolites - with special reference to glibenclamide

    Author : Anders Jönsson; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sekretion; Endokrinologi; secreting systems; diabetology; Endocrinology; diabetologi;

    Abstract : The pharmacodynamics (PD), pharmacokinetics (PK) and metabolism of the sulphonylurea(SU) and its metabolites (M1 and M2) , and of another SU, glipizide (Gz) were studied in diabetes patients and healthy volunteers. In one study Caucasians and Chinese were compared. READ MORE

  6. 34. Healthy Satiety Effects of Paleolithic diet on Satiety and Risk factors for Cardiovascular disease

    Author : Tommy Jönsson; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; diabetologi; sekretion; Endokrinologi; Cardiovascular Disease; Paleolithic Diet; Satiety; Endocrinology; diabetology; secreting systems; Kardiovaskulära systemet;

    Abstract : The prevalence of cardiovascular diseases (CVD) exhibits considerable variation across agrarian societies, whereas they are virtually absent in non-agrarian societies such as hunter-gatherer and horticultural societies. When looking for lifestyle factors which could promote CVD, it therefore seems logical to focus on the agrarian lifestyle and ways in which it departs from a non-agrarian lifestyle. READ MORE

  7. 35. Genetics of type 2 diabetes and the metabolic syndrome

    Author : Mia Klannemark; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; PDE3B; PPARG; LPL; metabolic syndrome; diabetes; genetic; HSL; UCP2; Endokrinologi; sekretion; diabetologi;

    Abstract : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. READ MORE