Search for dissertations about: "diazo-oxo-L-norleucine"

Found 1 swedish dissertation containing the word diazo-oxo-L-norleucine.

  1. 1. Specific anti-tumour effects of 6-diazo-5-oxo-L-norleucine (DON) on carcinoid tumour cells

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Feng Wu; Uppsala universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; carcinoid tumour; diazo-oxo-L-norleucine; mitochondria; apoptosis; PET; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Glutamine is essential for cell growth. 6-diazo-5-oxo-L-norleucine (DON) is a rather old anti-tumour drug developed as a glutamine antagonist. Previous clinical trials with DON, not including carcinoid tumours, did not prove convincing. Hence the drug was not further used. READ MORE