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Showing result 1 - 5 of 8 swedish dissertations matching the above criteria.

  2. 1. Modulators of UCP1-dependent thermogenesis : Glucocorticoids, diet and novel research models

    Author : Ineke H. N. Luijten; Jan Nedergaard; Onno Meijer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; brown adipose tissue; UCP1; glucocorticoids; diet-induced thermogenesis; obesity; physiology; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The activation and recruitment of brown adipose tissue (BAT) thermogenesis has been put forward as a promising strategy to reduce the disease burden of obesity and obesity-related diseases. Heat production by BAT can be attributed to the tissue-specific mitochondrial uncoupling protein 1 (UCP1). READ MORE

  4. 2. Energy flow and metabolic efficiency attributed to brown adipose tissue

    Author : Gabriella von Essen; Jan Nedergaard; Susanne Klaus; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brown adipose tissue; BAT; UCP1; diet-induced thermogenesis; DIT; obesity; high-fat diet; energy expenditure; fysiologi; Physiology;

    Abstract : The large capacity of brown adipose tissue (BAT) to expend energy as heat makes it an interesting potential player in weight regulation and other metabolic conditions. This is of particular interest as it has been recognized that adult humans possess BAT. READ MORE

  5. 3. Dietary, Pharmacological and Environmental Effects on Brown Adipose Tissue

    Author : Erik Lindsund; Tore Bengtsson; Jan Nedergaard; Karsten Kristiansen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Obesity; brown adipose tissue; uncoupling protein 1; moderate cold exposure; calorimetry; thyroxine; dietary protein; thermic effect of food; diet-induced thermogenesis; adrenergic stimulation; mice; physiology; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Obesity is a common health issue; over 12 % of the adult world population have obesity. Obesity has many co-morbidities including cardo-vascular diseases and diabetes. Obesity is the result of chronic positive energy balance, eating too much and expending too little. READ MORE

  6. 4. Novel lipid derivatives for health benefits : synthesis, analysis and effects in diet-induced obese mice

    Author : Samanthi Madawala; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Obesity is a public health concern and requires effective management with multiple approaches. Dietary supplements of bioactive compounds that can improve fatty acid oxidation and thermogenesis are currently in focus to develop anti-obese food ingredients/nutraceuticals without side-effects. READ MORE

  7. 5. The effect of various dietary fatty acids on adaptive thermogenesis

    Author : Gabriella von Essen; Jan Nedergaard; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fysiologi; Physiology;

    Abstract : Recently it has been revealed that brown adipose tissue (BAT) is present in adult humans and not, as thought before, only in infants and rodents. BAT, with a main function to generate heat, is also involved in energy metabolism by an adaptive response to eating, referred to as diet-induced thermogenesis (DIT). READ MORE