Search for dissertations about: "dietary antigens"

Showing result 1 - 5 of 9 swedish dissertations containing the words dietary antigens.

  1. 1. On the regulation of immune responses to dietary and self antigens

    Author : Susanne Lindgren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Tolerance; regulatory T cells; self antigens; oral tolerance; dietary antigens; intestinal epithelial cells; exosomes; Staphylococcus aureus enterotoxin A;

    Abstract : Regulatory mechanisms are necessary to avoid the misdirected aggressive immune responses responsible for the pathology seen in autoimmunity and allergy. Thymic-derived CD4+CD25+ regulatory T cells are indispensible for this regulation. We investigated if CD4+CD25+ Treg prevents auto-reactive responses in adult peripheral blood and cord blood. READ MORE

  2. 2. Crohn's disease : Studies on epidemiology, twins, aetiological factors and clinical course with special reference to smoking

    Author : Eva Lindberg; Linköpings universitet; []
    Keywords : Crohn s disease; epidemiology; incidence; prevalence; smoking; genetics; twins; dietary antigens; yeast; Saccharomyces cerevisiae; mannan; gliadin; betalactoglobulin; ovalbuntin; MEDICINE; MEDICIN;

    Abstract : In an epidemiological study of the incidence of Crohn's disease in Orebro county during the 25-year period 1963-1987, the mean annual incidence was 6.1/105 inhabitants. During the first five year period the mean incidence was 4.3 but during the following four quinquennia the incidence was stable at around 6. READ MORE

  3. 3. Dietary antibodies and gluten related seromarkers in children and young adults with cerebral palsy

    Author : Reidun Stenberg; Jens Schollin; Curt Tysk; Lotta Dahle; Claes Hallert; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cerebral palsy; children; celiac disease; glutensensitivity; brain; transglutaminase 2 and 6; malnutrition; casein; eggwhite laktoglobulin; Medicin; Medicine;

    Abstract : Background & Aims: Cerebral palsy (CP), the most common physical disorder in children that affect motor function, is associated with a low weight and height. Celiac disease (CD), an autoimmune disorder precipitated by ingestion of gluten, is another common chronic disease in children that has a negative impact on growth. READ MORE

  4. 4. Immunopathogenesis of Gai2-deficient mice. A model of inflammatory bowel disease

    Author : Lena Öhman; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory Bowel Disease; Mucosa; Apoptosis; Bordetella pertussis; G-protein;

    Abstract : The intestinal mucosa is the largest lymphoid organ in the body, and it simultaneously has to protect us from any pathogen that might enter the gastrointestinal tract as well as maintaining tolerance to most antigens, mainly in the form of dietary constituents and microbial products. A dysfunctional control of local intestinal immune responses may lead to development of Inflammatory Bowel Disease (IBD) - the common name for ulcerative colitis (UC) and Crohn´s disease (CD). READ MORE

  5. 5. Impact of genetic and environmental factors in intestinal inflammation

    Author : Oscar Eduardo Diaz Perez; Karolinska Institutet; Karolinska Institutet; []

    Abstract : The gastrointestinal tract, is continuously exposed to a wide variety of stimuli, including dietary-derived metabolites, environmental compounds and the microbiota. Since these antigens can be beneficial or detrimental for the organism, proper sensing of the luminal content is essential for orchestrating both pro-inflammatory and tolerogenic immune responses on demand and therefore, ensure the establishment of intestinal homeostasis. READ MORE