Search for dissertations about: "differentiation."

Showing result 21 - 25 of 1988 swedish dissertations containing the word differentiation..

  2. 21. On the role of the retinoblastoma tumor suppressor gene in hematopoietic differentiation

    Author : Gösta Bergh; Helsingborg Kliniska Vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antisense; leukemia; cell cycle; differentiation; hematopoiesis; p16; p53; tumor suppressor genes; RB; oligonucleotides; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Abstract : The aim of this study was to investigate the role of some tumor suppressor gene products (with emphasis on the retinoblastoma suppressor gene product) in the regulation of differentiation and proliferation in leukemic and normal hematopoietic cells. For this purpose, the expression of the tumor suppressor genes RB, p53 and p16 were artificially altered. READ MORE

  4. 22. Regulation of growth, differentiation and survival of B-chronic lymphocytic leukemia cells

    Author : Ola Söderberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; B-CLL; B cells; IL-2; IL-4; IL-10; IL-15; CD40-stimulation; SAC; Thioredoxin; proliferation; differentiation; survival; in vitro; EBV; Patologi; Pathology; Patologi; Pathology; patologi;

    Abstract : Chronic lymphocytic leukemia of B cell type (B-CLL) is the most commonform of leukemia in the Western countries. The signals regulating theexpansion of the B-CLL clone in vivo is yet far from being fully understood. READ MORE

  5. 23. The role of nuclear envelope proteins in chromatin organization, differentiation and disease

    Author : Cecilia Bergqvist; Einar Hallberg; Philippe Collas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nuclear envelope proteins; chromatin organization; epigenetics; differentiation; quantitative image analysis; Samp1; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : In eukaryotes the genetic material is separated from the cytoplasm by the nuclear envelope (NE), consisting of the outer and inner nuclear membrane, the nuclear lamina and the nuclear pores. The genetic material is highly structured with transcriptionally inactive heterochromatin enriched at the nuclear periphery and transcriptionally active euchromatin in the nuclear interior. READ MORE

  6. 24. Mechanisms of stretch-induced growth and contractile differentiation in vascular smooth muscle

    Author : Asad Zeidan; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysiologi; Physiology; SM22a; ERK1 2; caveolae; stretch; Smooth muscle; differentiation;

    Abstract : Vascular smooth muscle can adapt to increased intraluminal pressure by remodelling and hypertrophy, as seen in hypertension. The molecular mechanisms responsible for this are still incompletely characterized. READ MORE

  7. 25. Differentiation, didactics and inequality: How rich and poor populations are educatied for sustainability

    Author : Linus Bylund; Göteborgs universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; biopolitics; didactics; differentiation; ESD; geography of education; inequality; ; education for sustainable development;

    Abstract : In recent decades, education for sustainable development (ESD) has gained prominence as an urgent educational imperative. Although ESD is championed by UNESCO as contributing to a just, and sustainable future, the question remains open whether it is possible to address all of humanity in a just and equitable manner in a highly unequal world. READ MORE