Search for dissertations about: "digital PCR"

Showing result 16 - 20 of 99 swedish dissertations containing the words digital PCR.

  2. 16. Fungal DNA, Mould, Dampness and Allergens in Schools and Day Care Centers and Respiratory Health

    Author : Guihong Cai; Dan Norbäck; Christer Janson; Nils Åberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Day care centers; Quantitative PCR; Fungal DNA; Allergens; Indoor environment; Building dampness; Bacteria; Mycotoxins; Respiratory symptoms; Asthma; School environment; Viable moulds; School children; Occupational and Environmental Medicine; Arbets- och miljömedicin;

    Abstract : Day care centers and schools are important environments for children, but few epidemiological studies exist from these environments. Mould, dampness, fungal DNA and allergens levels in these environments and respiratory health effects in school children were investigated in this thesis. READ MORE

  4. 17. Self-rated health and respiratory symptoms among civil aviation pilots : Occupational and non-occupational risk factors

    Author : Xi Fu; Dan Norbäck; Christer Janson; Berndt Stenberg; Uppsala universitet; []
    Keywords : Civil Aviation; Aircraft pilot; Indoor environment; Self-rated health SRH ; Respiratory health; Asthma; Rhinitis; Headache; Fatigue; Insom-nia; Body mass index BMI ; Sense of Coherence SOC ; Psychosocial work environment; Quantitative PCR; Fungal DNA; Volatile organic compounds of microbial origin MVOC ; Cat allergen; Dog allergen; Horse allergen;

    Abstract : There is concern about the indoor environment in aircraft but few stud-ies exist on self-rated health (SRH) and respiratory symptoms among pilots. Occupational and non-occupational risk factors for SRH, respira-tory symptoms and other symptoms among commercial pilots were investigated in this thesis. READ MORE

  5. 18. Radiolabelled Oligonucleotides for Evaluation of in vivo Hybridisation Utilising PET Methodology

    Author : Gábor Lendvai; Mats Bergström; Sergio Estrada; Barbro Eriksson; Raymond Josephsson; Bertrand Tavitian; Uppsala universitet; []
    Keywords : Molecular medicine; Gene expression; Antisense oligonucleotides; Positron emission tomography; In vivo hybridisation; In vivo biodistribution; Chromogranin-A; 68Ga; RT-PCR; Scavenger receptors; Molekylärmedicin;

    Abstract : Antisense oligonucleotides (ODN) may interfere in gene expression on the basis of hybridising to its complementary messenger RNA (mRNA) sequence in the cell thereby preventing the synthesis of the peptide. Therefore, these ODNs may be potential drugs to treat human diseases by “knocking down” the expression of responsible genes or correcting the maturation process of mRNA in the field called antisense therapy. READ MORE

  6. 19. The Immune Response to One-Lung Ventilation : Clinical and Experimental Studies

    Author : Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; Medical laboratory science; Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

    Abstract : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. READ MORE

  7. 20. Qualitative and Quantitative Assessment of Cytochromes P450 mRNA in Human : Studies in the Liver, Blood and Gastrointestinal Mucosa

    Author : Mari Thörn; Lars Lööf; Anders Rane; Ellen Vinge; Uppsala universitet; []
    Keywords : Medical sciences; cytochrome P450; CYP1A2; CYP1B1; CYP2E1; CYP3A4; CYP3A5; P-gp; gene expression; RT-PCR; liver; blood; gastrointestinal mucosa; MEDICIN OCH VÅRD; MEDICINE; MEDICIN;

    Abstract : Drugs and other foreign compounds must often be metabolised before they can be excreted from the body. One enzyme system that is responsible for this is the cytochrome P450 gene family (CYP). READ MORE