Search for dissertations about: "digital PCR"

Showing result 21 - 25 of 99 swedish dissertations containing the words digital PCR.

  2. 21. The Origin of the Genus Flavivirus and the Ecology of Tick-Borne Pathogens

    Author : John H.-O. Pettersson; Thomas Jaenson; Sven Bergström; Kenneth Nilsson; Mikael Thollesson; Per-Eric Lindgren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Flavivirus; Virus dating; Molecular dating; Biogeography; Ixodes ricinus; Minimum infection rate; TBE; Tick-borne encephalitis virus; Rickettsia helvetica; Anaplasma phagocytophilum; Infection prevalence; RT-PCR; Biology with specialization in Systematics; Biologi med inriktning mot systematik;

    Abstract : The present thesis examines questions related to the temporal origin of the Flavivirus genus and the ecology of tick-borne pathogens. In the first study, we date the origin and divergence time of the Flavivirus genus. It has been argued that the first flaviviruses originated after the last glacial maximum. READ MORE

  4. 22. Development of Molecular Biology and Bioinformatics Tools : From Hydrogen Evolution to Cell Division in Cyanobacteria

    Author : Fernando Lopes Pinto; Peter Lindblad; Röbbe Wünschiers; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cyanobacteria; hydrogen; RNA; bioinformatics; RT-PCR; RACE; transcription; Molecular biology; Molekylärbiologi; Bioinformatics; Bioinformatik; Molecular Biology; Molekylärbiologi;

    Abstract : The use of fossil fuels presents a particularly interesting challenge - our society strongly depends on coal and oil, but we are aware that their use is damaging the environment. Currently, this awareness is gaining momentum, and pressure to evolve towards an energetically cleaner planet is very strong. READ MORE

  5. 23. Molecular detection and epidemiological studies of atypical bacteria causing respiratory tract infections

    Author : Karolina Gullsby; Kåre Bondeson; Björn Olsen; Puolakkainen Mirja; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chlamydia pneumoniae; Mycoplasma pneumoniae; Bordetella pertussis; real-time PCR; P1 typing; MLVA; whole-genome sequencing; macrolide resistance; molecular diagnostics; molecular epidemiology;

    Abstract : Respiratory infections are common causes of morbidity and mortality. Chlamydia pneumoniae, Mycoplasma pneumoniae and Bordetella pertussis cause respiratory infection, often with similar symptoms. Molecular diagnostic methods are preferred since these bacteria are difficult to culture. READ MORE

  6. 24. Gene Expression in the Brains of Two Lines of Chicken Divergently Selected for High and Low Body Weight

    Author : Sojeong Ka; Finn Hallböök; Tom Porter; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chicken; juvenile body weight; divergent selection; gene expression; DNA microarray; quantitiative RT-PCR; hypothalamus; neural plasticity; melanocortin system; endogenous retrovirus; carnitine palmitoyltransferase-1b; Neurobiology; Neurobiologi; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Abstract : Artificial divergent selection of chickens for high and low body weight at 8 weeks of age has produced two lines: the high (HWS) and low (LWS) body weight chicken lines. In addition to the difference in body weight, the lines show extreme differences in feeding behaviour and body composition. READ MORE

  7. 25. Developmental Aspects of Drug Transport Across the Blood-Brain Barrier

    Author : Jörgen Bengtsson; Margareta Hammarlund-Udenaes; Ann-Cathrin Engwall; Sven Björkman; Elizabeth C.M. de Lange; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; development; active transport; tight junction proteins; microdialysis; recovery; morphine; nitrofurantoin; Bcrp; microarray; real-time PCR; in vitro; in vivo; LC-MS MS; Biopharmacy; Biofarmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : The developmental aspect of drug transport across the blood-brain barrier (BBB) was investigated. Microdialysis was used to study unbound morphine BBB transport at different ages in sheep. An in vitro study was performed to find differentially expressed genes in brain capillary-rich fractions of the brain in rats of different ages. READ MORE