Search for dissertations about: "digital generation culture"

Showing result 1 - 5 of 9 swedish dissertations containing the words digital generation culture.

  2. 1. OPENING THE BOX : Exploring the presumptions about the 'Net Generation'

    Author : Sheila Zimic; Bo Sundgren; Katarina Lindblad-Gidlund; Patrik Hernwall; Mittuniversitetet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Net Generation ; presumptions; deconstruction; digital competence; digital participation; Informatics; computer and systems science; Informatik; data- och systemvetenskap;

    Abstract : There are many names or labels which refer to the generation growing up with digital media and these include labels such as ‘Net Generation’ (Tapscott, 1998), ‘digital natives’ (Prensky, 2001), ‘cyberkids’ (Holloway, 2003) and ‘MySpacegeneration’ (Rosen, 2008). The core idea behind these labels is that young people who have grown up surrounded by digital technology are very different to previous generations in their way of using and even thinking about the new digital technology. READ MORE

  4. 2. Glioblastoma heterogeneity and plasticity : Investigating the roles of BMP4 and SOX2

    Author : Erika Dalmo; Bengt Westermark; Fredrik J. Swartling; Lene Uhrbom; Ana Martin-Villalba; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; SOX2; BMP4; senescence; plasticity; Oncology; Onkologi; Medicinsk vetenskap; Medical Science; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : The malignant primary brain tumor glioblastoma has a dismal prognosis and is distinguished by its heterogeneous character. Current treatment with surgical resection, radiotherapy and adjuvant chemotherapy with the alkylating agent temozolomide does not provide a cure, but simply prolongs survival by a few months. READ MORE

  5. 3. CRISPR/Cas9-based therapies and the role of astrocytes in Alzheimer’s disease and Parkinson’s disease

    Author : Evangelos Konstantinidis; Martin Ingelsson; Anna Erlandsson; Vilmantas Giedraitis; Magnus Essand; Harald Steiner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Parkinson s disease; gene editing; CRISPR Cas9; amyloid-beta; astrocytes; neurons; iPSCs; electrophysiology;

    Abstract : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders. Whereas the AD brain features plaques of amyloid-beta (Aβ) and neurofibrillary tangles of tau, the PD brain is characterized by Lewy bodies and Lewy neurites containing α-synuclein (αSyn). READ MORE

  6. 4. Characterization of the novel “Uppsala mutation” causing a familial form of early onset Alzheimer’s disease

    Author : María Pagnon de la Vega; Martin Ingelsson; Dag Sehlin; Vilmantas Giedraitis; Gunnar Gouras; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; neurodegeneration; amyloid precursor protein; APP processing; amyloid beta; transgenic mouse model;

    Abstract : The Alzheimer’s disease (AD) brain displays extracellular plaques of amyloid-β (Aβ), neurofibrillary tangles of tau and neuronal loss. The 40-42 amino acid Aβ peptide is formed from the amyloid precursor protein (APP) by β-secretase and γ-secretase, while α-secretase prevents Aβ generation. READ MORE

  7. 5. CAR T cells for Immunotherapy of Cancer

    Author : Tina Sarén; Magnus Essand; Martin Pule; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chimeric antigen receptor CAR -T cells; Cancer immunotherapy; NAP; Tonic signaling; T cell exhaustion; B cell lymphoma; clinical trial; glioblastoma;

    Abstract : In recent years, immunotherapy has revolutionized cancer treatment by prolonging survival and even curing patients lacking other available therapies. Besides immune checkpoint inhibitors, one of the major advances is attributed to the success of chimeric antigen receptor (CAR)-T cell therapy in treating patients with B-cell malignancies. READ MORE