Search for dissertations about: "digital quantification"

Showing result 11 - 15 of 153 swedish dissertations containing the words digital quantification.

2. 11. Methodological aspects of quantitative cardiac molecular imaging

   Author : Tanja Kero; Mark Lubberink; Håkan Ahlström; Elin Trägårdh; Uppsala universitet; []
   Keywords : PET; cardiac amyloidosis; 11C-PIB; retention index; standardized uptake value; PET-MR; MRI; myocardial blood flow; 15O-water; quantification; quantitative modeling;

   Abstract : The objective of this research was to facilitate the use of quantitative cardiac molecular imaging by developing and validating methods and applications. More specifically:we determined the optimal tracer kinetic model for analysis of 11C-PIB and evaluated the performance of two simpler measures, retention index (RI) and standardized uptake value (SUV), in the quantification of cardiac 11C-PIB uptake in amyloidosis. READ MORE

4. 12. Evaluation of Regularized Image Reconstruction for Clinical Positron Emission Tomography

   Author : Elin Lindström; Mark Lubberink; Jens Sörensen; Anders Sundin; Anne Larsson Strömvall; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography; PET CT; molecular imaging; image reconstruction; regularized reconstruction; quantification; oncology; neurology; cardiology; Medicinsk radiofysik; Medical Radiophysics;

   Abstract : Positron emission tomography (PET) combined with computed tomography (CT) is a widely used noninvasive molecular imaging modality with a broad range of clinical applications in oncology, neurology, and cardiology. Producing imperative image quality and accurate quantification are important driving forces behind the technological advances within PET image reconstruction and system development. READ MORE

5. 13. Assessment of attenuation correction methods for quantitative neuro-PET/MR

   Author : Joao M. Sousa; Mark Lubberink; Lieuwe Appel; Håkan Ahlström; Mathias Engström; Ivo Rausch; Radiologi Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET; MRI; attenuation correction; 68Ge transmission; quantification; 11C-PE2I; MRAC; DAT; CBF; Medicinsk radiofysik; Medical Radiophysics;

   Abstract : Hybrid PET/magnetic resonance (MR) can provide physiological, functional, and structural information simultaneously, facilitating research in neurological disorders. For quantitative PET, correction for photon attenuation (AC) is necessary. READ MORE

6. 14. Method Development in Quantitative and Structural Proteomics using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

   Author : Charlotte Hagman; Per Håkansson; Jonas Bergquist; Jos Buijs; Michael Przybylski; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Cerebrospinal Fluid; Electrospray Ionization; Fourier Transform Ion Cyclotron Resonance Mass Spectrometry; Global Markers; High Performance Liquid Chromatography; Gas-Phase Exchange; Hydrogen Deuterium Exchange; Plasma; Protoemics; Quantification; Structural Elucidation; Bioteknik; Bioengineering; Bioteknik;

   Abstract : In this thesis, methods for studying different aspects of proteomics were developed with Fourier Transform Ion Cyclotron Resonance, (FTICR), mass spectrometry. The FTICR technique provides ultra-high mass resolving power, mass accuracy at sub ppm level and sensitivity in the attomole region. READ MORE

7. 15. Improved methodologies for molecular detection and quantification of viruses in food

   Author : Sofia Persson; Patrik Ellström; Magnus Simonsson; Wim van der Poel; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; foodborne virus; digital PCR; real-time PCR; validation; assay design; food safety; Medicinsk vetenskap; Medical Science;

   Abstract : Foodborne viruses such as norovirus, hepatitis A virus and hepatitis E virus cause a high burden of disease worldwide. Reverse transcription (RT) quantitative real-time PCR (qPCR) is the current standard method for monitoring viral contamination in the food chain. READ MORE