Search for dissertations about: "dihalo-analogues"
Found 2 swedish dissertations containing the word dihalo-analogues.
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1. Synthesis and applications of analogues of Tröger's base as molecular tubes, receptor and ligands
Abstract : Tröger’s base was synthesized for the first time in 1887. The molecule is rigid, C2-symmetric and has a 90° angle, forming a chiral hydrophobic pocket. In this thesis, the synthesis of new analogues of Tröger’s base is described. 2- and 3-halo-substituted anilines have for the first time been condensed to Tröger’s base analogues. READ MORE
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2. Making Analogues of Tröger's Base – Fused oligomers, endo/exo isomers and twisted amides
Abstract : The centenarian Tröger’s base (TB) was envisaged as scaffold for the construction of tubular-shaped cleft molecules due to its the remarkable structural properties. This endeavor started with the synthesis of the three possible diastereomers of a linear symmetrically fused tris-TB analogue, the anti-anti, the syn-syn, and the syn-anti. READ MORE