Search for dissertations about: "dimerisation"

Showing result 1 - 5 of 18 swedish dissertations containing the word dimerisation.

  1. 1. Heparan Sulfate Regulation of Fibroblast Growth Factor (FGF) Receptor-1 Signal Transduction

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lars Lundin; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; FGF; FGFR; dimerisation; signal transduction; heparan sulfate; proteoglycan; heparin; VEGF; embryonal stem cell; endothelial cell; differentiation; Patologi; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi;

    Abstract : Fibroblast growth factors (FGFs) constitute a family (currently FGF-1 to FGF-23) of polypeptides that are essential in embryonal development and adult physiology, in animals from nematodes to humans. FGFs bind to four receptor tyrosine kinases, denoted FGFR-1 to FGFR-4. READ MORE

  2. 2. Local and global contaminants in Swedish waters studies on PCBs, DDTs, 4,5,6-trichloroguaiacol and their transformation products in fish and sediments

    University dissertation from Stockholm : Department of Environmental Chemistry, Stockholm Univeristy

    Author : Maria Söderström; Stockholms universitet.; [2002]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PCB; DDT; HCB; trichloroguaiacol; transformation products; dimerisation; bromination; environmental pollutants; eutrophication; lakes; fresh water; baltic sea; monitoring; sediments; fish; phytoplankton; PCB; DDT; HCB; triklorguajakol; omvandlingsprodukter; dimerisering; bromering; miljöföroreningar; eutrofiering; sjöar; sötvatten; östersjön; miljöövervakning; sediment; fisk; fytoplankton; Environmental Chemistry; miljökemi;

    Abstract : This thesis is focused on studies on the environmental fate and methodological improvements for determination of the global contaminants, PCBs and DDTs, and locally discharged phenolics, e.g. 4,5,6-trichloroguaiacol (4,5,6-TCG), and their transformation products. READ MORE

  3. 3. LL-37-derived cyclic antimicrobial drug leads Design, synthesis, activity and different ways of creating them 

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Taj Muhammad; Uppsala universitet.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptide; host defense; antimicrobial; LL-37; KR-12; peptide cyclisation; peptide dimerisation; croos-linking; cyanobactin-macrocyclase; PatGmac; butelase 1; enzymatic cyclisation; immobilisation; Farmakognosi; Pharmacognosy;

    Abstract : In an era where last-line antibiotics are failing, one of the powerful approaches to develop novel therapeutic agents is to turn back to nature in order to identify possible drug candidates. Among the potential candidates, antimicrobial peptides (AMPs) have garnered much attention as an antimicrobial. READ MORE

  4. 4. Fluorescence studies of complex systems organisation of biomolecules

    University dissertation from Umeå : Kemi

    Author : Denys Marushchak; Umeå universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fluorescence anisotropy; BODIPY; homo and hetero dimerisation; protein aggregates; protein polymer structures; actin polymerisation; FRET; donor–acceptor energy transfer DAET; donor-donor energy migration DDEM; homotransfer; Monte Carlo simulation; MC; Brownian dynamics; BD; Genetic Algorithm; GA.; Ganglioside GM1; NATURAL SCIENCES Chemistry Physical chemistry Biophysical chemistry; NATURVETENSKAP Kemi Fysikalisk kemi Biofysikalisk kemi;

    Abstract : The homo and hetero dimerisation of two spectroscopically different chromophores were studied, namely: 4,4-difluoro-4-bora-3a,4a-diazas-indacene (g-BODIPY) and its 5-styryl-derivative (r-BODIPY). Various spectroscopic properties of the r-BODIPY in different common solvents were determined. READ MORE

  5. 5. Mechanism of conditional regulation of the bHLH/PAS dioxin receptor

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Jacqueline McGuire; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : J. McGuire The intracellular dioxin receptor is a bHLH/PAS protein which mediates signal transduction by dioxin and upon heterodimerisation with the bHLH/PAS partner factor Arnt, functions as a ligand-activated transcription factor by binding to specific xenobiotic response elements in promoters of target genes. READ MORE