Search for dissertations about: "dimerisation"

Showing result 11 - 15 of 18 swedish dissertations containing the word dimerisation.

  1. 11. Protein folding studies of human superoxide dismutase and ALS associated mutants

    Author : Mikael Lindberg; Mikael Oliveberg; Jane Clarke; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; superoxide dismutase; ALS; protein folding; equilibrium titration; protein stability; apo protein; disulphide bridge; chevron plot; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. READ MORE

  2. 12. Development of Novel Hydroporphyrins for Light Harvesting and Sensitising NIR Lanthanide Luminescence

    Author : Ruisheng Xiong; Eszter Borbas; Christian Brückner; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chlorin; hydroporphyrin; chlorophyll analogues; light harvesting; lanthanide luminescence; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Abstract : Chlorins, as the core structures of chlorophylls, have been extensively studied for harvesting solar energy, fluorescent imaging and photodynamic therapy against cancer. This thesis is concerned with design and synthesis of novel chlorins as antennae for harvesting light and sensitising near infrared lanthanide luminescence. READ MORE

  3. 13. Synthesis and Energy Transfer Studies of a Donor-Host-Acceptor Triad

    Author : Jerker Mårtensson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; orientation factor; self-assembly; porphyrin; cations; F #246; rster; dimer; donor-host-acceptor triad; energy transfer; degenerate transition; diaza-crown ether;

    Abstract : This dissertation describes the synthesis of a donor-host-acceptor triad, D-H-A, and its self-assembly into a well-ordered dimer. The energy transfer (EnT) properties of D-H-A as it is, in the presence of a variety of guest molecules and in the dimeric form are presented. READ MORE

  4. 14. Studies of the vascular endothelial growth factors, VEGFs, and their receptors, focusing on VEGF-B

    Author : Birgitta Olofsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : vasculogenesis; angiogenesis; VEGF; VEGF-B; VEGF receptors; neuropilin;

    Abstract : The inner lining of all blood- and lymphatic vessels are composed of endothelial cells. Their growth and differentiation are in part regulated by polypeptide growth factors and their receptors. READ MORE

  5. 15. Hypoxia inducible factor 1alpha : molecular mechanisms of regulation

    Author : William J Wilson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hypoxia-Inducible Factor 1alpha (HIF-1alpha) is an important protein in the homeostatic control of genes in response to low oxygen, or hypoxia. It is thus also a key factor in the regulation of angiogenesis in response to hypoxia, including induction of vascular endothelial growth factor (VEGF) gene expression. READ MORE