Search for dissertations about: "direct immunofluorescence in dermatology"

Found 1 swedish dissertation containing the words direct immunofluorescence in dermatology.

2. 1. Autoantibodies and the Type I Interferon System in the Etiopathogenesis of Systemic Lupus Erythematosus

   Author : Stina Blomberg; Johan Frostegård; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Systemic lupus erythematosus; type I interferon; interferon inducer; dendritic cell; natural interferon-alpha producing cell; immune complex; SSA Ro; dsDNA; BDCA; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicine; medicin;

   Abstract : In sera remitted for anti-nuclear antibody (ANA) analysis, the supplement of a sensitive anti-SSA/Ro ELISA to the conventional ANA screening by immunofluorescence (IF) revealed that one fourth of the individuals with IF-ANA negative, but SSA/Ro ELISA positive sera, had systemic lupus erythematosus (SLE) or cutaneous LE. Consequently, adding a sensitive anti-SSA/Ro ELISA to the ANA screening is valuable for the serological detection of ANA negative SLE/LE patients. READ MORE